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  • 8.52113 - Fmoc-Asp(biotinyl-PEG)-OH

8.52113 EMD Millipore



Synonym: N-α-Fmoc-N-γ-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)-ethoxy)-ethoxy)-propyl)-L-asparagine

  • Linear Formula C₃₉H₅₃N₅O₁₀S

  • Molecular Weight 783.93 g/mol



Related Categories Amino Acids & Derivatives, Aspartic Acid, Chemical Biology, Chemical Synthesis, Peptide Chemistry More...
brand family   Novabiochem
packaging   1 g in Glass bottle (8521130001)
  500 mg in Glass bottle (8521138500)
shipped in   ambient
storage temp.   Store at +2°C to +8°C.
specifications   Colour (visual): white to slight yellow to beige
  Appearance of substance (visual): powder
  Identity (IR): passes test
  Enantiomeric purity: ≥ 99.5 % (a/a)
  Purity (TLC(CMA2)): ≥ 98 %
  Assay (HPLC, area%): ≥ 95.0 % (a/a)
  Solubility (1 mmole in 2 ml DMF): clearly soluble
  For TLC-Systems see our General Catalog


Background information

In contrast to Fmoc-Lys(biotin)-OH, this novel biotin-labeled amino acid has excellent solubility in DMF and other solvents used in SPPS [1]. The PEG-spacer restricts hindrance between the peptide and avidin, leading to better biotin binding. Furthermore, the hydrophilic nature of the PEG minimizes non-specific interactions that can arise from the spacer group becoming buried in the hydrophobic pocket of proteins.

The product number for this product was previously 04-12-1279.

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Safety Information

HS Code 
2934 99 90
Storage class 
10 - 13 Other liquids and solids
WGK 2 water endangering
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