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8.52114 EMD Millipore

Fmoc-Ile-(Dmb)Gly-OH

Novabiochem®

Synonym: N-α-Fmoc-L-Isoleucyl-N-α-(2,4-dimethoxybenzyl)-glycine

  • Linear Formula C₃₂H₃₆N₂O₇

  • Molecular Weight 560.64 g/mol

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Properties

Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Peptide Chemistry
brand family   Novabiochem
packaging   1 g in Glass bottle (8521140001)
  5 g in Glass bottle (8521140005)
shipped in   ambient
storage temp.   Store at +2°C to +8°C.
specifications   Colour (visual): white to slight yellow to beige
  Appearance of substance (visual): powder
  Identity (IR): passes test
  Optical rotation α 25/D (c=1 in methanol): -34.0 - -28.0 °
  Purity (TLC(157A)): ≥ 98 %
  Assay (HPLC, area%): ≥ 96.0 % (a/a)
  Solubility (1 mmole in 2 ml DMF): clearly soluble
  Assay (acidimetric): ≥ 90.0 %
  Water (K. F.): ≤ 1.50 %
  For TLC-Systems see our General Catalog

Description

Background information

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP®/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.



The product number for this product was previously 04-12-1280.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".

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Safety Information

HS Code 
2924 29 70
Storage class 
10 - 13 Other liquids and solids
WGK 
WGK 2 water endangering
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