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8.52261 EMD Millipore

Di-tert-butyl dicarbonate

Di-tert-butyl dicarbonate Novabiochem®. CAS 24424-99-5, molar mass 218.25 g/mol., Novabiochem®

Synonym: Di-tert-butyl dicarbonate, Di-tert-butyl pyrocarbonate

  • CAS Number 24424-99-5

  • Linear Formula C₁₀H₁₈O₅

  • Molecular Weight 218.25 g/mol

  •  EC Number 246-240-1



Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Peptide Chemistry
brand family   Novabiochem
packaging   100 g in Glass bottle (8522610100)
  25 g in Glass bottle (8522610025)
bp   56 - 57 °C (0.7 hPa)
density   1.02 g/cm3 (20 °C)
flash point   37 °C
autoignition temp.   460 °C
mp   20 - 24 °C
LD 50 oral   LD50 Rat > 5000 mg/kg
LD 50 dermal   LD50 Rabbit > 2000 mg/kg
shipped in   ambient
storage temp.   Store at +2°C to +8°C.
specifications   Colour (visual): white
  Appearance of substance (visual): crystal to crystalline solid
  Assay (GC, area%): ≥ 97.0 % (a/a)
  Identity (IR): passes test


Background information

Reagent for introduction of the Boc protecting group .

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Safety & Documentation

Safety Information

HS Code 
2920 90 10
Hazard Statement(s) 
H226: Flammable liquid and vapour.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H330: Fatal if inhaled.
Precautionary Statement(s) 
P210: Keep away from heat.
P280: Wear protective gloves.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P310: IF exposed or concerned: immediately call a POISON CENTER or doctor/ physician.
Storage class 
3 Flammable liquids
WGK 2 water endangering
Hazard Pictogram(s) 
GHS02  GHS02
Hazard Pictogram(s) 
GHS06  GHS06
Hazard Symbols 
Very toxic  Very toxic
Declaration (railroad and road) ADR, RID 
UN 2929 , 6.1 (3), II
Declaration (transport by air) IATA-DGR 
UN 2929 , 6.1 (3), II
Declaration (transport by sea) IMDG-Code 
UN 2929 , 6.1 (3), II
Categories of danger 
flammable, very toxic, irritant, sensitizing
R Phrase 
R 10-26-36/38-43
Flammable.Very toxic by inhalation.Irritating to eyes and skin.May cause sensitisation by skin contact.
S Phrase 
S 28-36/37-45
After contact with skin, wash immediately with plenty of water.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
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