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8.55051 EMD Millipore

Biotin NovaTag™ resin


Synonym: N-Biotin-NÆ-Fmoc-ethylenediamine MPB-AM resin



brand family   Novabiochem
packaging   1 g in Glass bottle (8550510001)
  500 mg in Glass bottle (8550518500)
shipped in   ambient
storage temp.   Store at -15°C to -25°C.
specifications   Colour (visual): white to light yellow to beige
  Appearance of substance (visual): beads
  Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.35 - 0.65 mmol/g
  Swelling Volume (in DMF): lot specific result
  The polymer metrix is copoly (styrene - 1% DVB), 100 - 200 mesh.


Background information

Biotin NovaTag™ resin is an ideal tool for the synthesis of peptides labeled iwth biotin. As the biotin moiety is incorporated into the linker, its use eliminates the problems associated with biotin-labeling of peptides, namely poor solubility and sluggish coupling kinetics of biotin and its derivatives. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the peptide labeled with biotin. For a recent applications see [1, 2].

The product number for this product was previously 04-12-3901.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".

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Safety Information

HS Code 
3903 90 90
Storage class 
10 - 13 Other liquids and solids
WGK 1 slightly water endangering
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