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8.55053 EMD Millipore

Dnp NovaTag™ resin

Novabiochem®

Synonym: N-Dnp-NÆ-Fmoc-ethylenediamine MPB-AM resin

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Properties

brand family   Novabiochem
packaging   100 mg in Glass bottle (8550538100)
  500 mg in Glass bottle (8550538500)
shipped in   ambient
storage temp.   Store at -15°C to -25°C.
specifications   Colour (visual): white to yellow to beige
  Appearance of substance (visual): beads
  Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
  Swelling Volume (in DMF): lot specific result
  The polymer matrix is copoly styrene - 1 % DVB 100 - 200 mesh

Description

Background information

Dnp NovaTag™ resin is an ideal tool for the synthesis of FRET peptide substrates based on the 7-methoxycoumarin (Mca) and 2,4-dintrophenyl (Dnp) fluorophore/quench pair. The resin pre-loaded with the Dnp quencher group can be used direcly in Fmoc SPPS. Following peptide assembly, the Mca group is coupled to the N-terminal N-amino group using Mca-OSu, or introduced to a side-chain of Lys using Fmoc-Lys(Mca)-OH, to give after TFA cleavage the desired FRET peptide substrate.

The product number for this product was previously 04-12-3903.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".

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Safety & Documentation

Safety Information

HS Code 
3903 90 90
Storage class 
10 - 13 Other liquids and solids
WGK 
WGK 1 slightly water endangering
Protocols & Articles
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