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8.55084 EMD Millipore

Aminomethyl NovaGel™

Novabiochem®

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Properties

brand family   Novabiochem
packaging   1 g in Plastic bottle (8550840001)
  25 g in Plastic bottle (8550840025)
  5 g in Plastic bottle (8550840005)
shipped in   ambient
storage temp.   Store at +2°C to +8°C.
specifications   Colour (visual): white to yellow to beige
  Appearance of substance (visual): beads
  Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.60 - 0.90 mmol/g
  TNBS-Test: passes test
  Swelling Volume (in DMF): lot specific result
  The PEG-PS resin is prepared from aminomethyl copoly (Styrene 1% DVB), 100 - 200 mesh.

Description

Background information

Aminomethyl NovaGel™ is a PEG-PS resin which has been designed to meet the requirements of organic chemists for resins of high substitution coupled with broad solvent compatibility. This support has a nominal loading of 0.7 mmole/g – almost twice that of comparable resins – but still retains most of the swelling characteristics of conventional PEG-PS supports. It is prepared from a special high-swell version of AM resin by partial derivatization with methyl-PEG-p-nitrophenylcarbonate [1]. Resin functionality is provided by residual aminomethyl groups.

The urethane linkage between the PEG and the base resin is stable to strongly acidic, basic and reducing conditions, ensuring minimal loss of PEG chains during synthesis. Furthermore, because the linker is not attached to the end of the PEG chains, if leaching of PEG does occur, the product is not contaminated with U.V. absorbing linker-PEG fragments which can complicate the nmr spectra and HPLC profiles of products obtained with other PEG-PS supports.

The product number for this product was previously 01-64-0283.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".

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Safety & Documentation

Safety Information

HS Code 
3903 90 90
Storage class 
10 - 13 Other liquids and solids
WGK 
WGK 1 slightly water endangering
Protocols & Articles
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