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01885 Sigma-Aldrich

Docetaxel

purum, ≥97.0% (HPLC)

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Properties

Related Categories Antibiotics, Apoptosis and Cell Cycle, Cell Biology, Cell Signaling and Neuroscience, Other Apoptosis Related Reagents More...
InChI Key   ZDZOTLJHXYCWBA-VCVYQWHSSA-N
grade   purum
assay   ≥97.0% (HPLC)
impurities   ~6% water
mp   186-192 °C (dec.)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Docetaxel is a taxane anti-cancer agent related to paclitaxel. It binds to and stabilizes the β−tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest and apoptosis.

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Docetaxel can be used to study antibiotics, cell biology, cell signaling, neuroscience and apoptosis and the cell cycle. Docetaxel has been used to study the prevention of chemotherapy-induced alopecia, as well as the treatment of non-small-cell lung cancer in patients contraindicated for standard chemotherapy. Docetaxel has also been used to study the role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




Flow Cytometry Instruments
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DA4172750

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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