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03395 Sigma-Aldrich

Poly(ethylene glycol)

tested according to Ph.Eur., 1,000

Synonym: Macrogol 1000, PEG

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Properties

Related Categories Analytical/Chromatography, Essential Chemicals, Materials Science, PEG and Oligo Ethylene Glycol, Pharmacopoeia,
vapor density   >1 (vs air)
vapor pressure   <0.01 mmHg ( 20 °C)
form   waxy solid
autoignition temp.   581 °F
pharmacopeia   testing conforms to Pharmacopeia
mol wt   mol wt 950-1050
solubility   aliphatic hydrocarbons: slightly soluble
  organic solvents: soluble

Description

Preparation Note

Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.

Application

Poly(ethylene glycol) is a chemical fusogen, which mediates the premature chromosome condensation induction in human and rat lymphocytes as well as in rodent spleen cells, and spleen and whole body cells of newborn mice.

Biochem/physiol Actions

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
TQ3500000
Flash Point(F) 
444.2 °F
Flash Point(C) 
229 °C

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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