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03701 Sigma-Aldrich

Ethylenediaminetetraacetic acid tetrasodium salt hydrate

≥97.0% (KT)

Synonym: EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate

  • CAS Number 194491-31-1

  • Linear Formula (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O

  • Molecular Weight 380.17 (anhydrous basis)

  •  Beilstein Registry Number 3861753

  •  EC Number 200-573-9

  •  MDL number MFCD00150025

  •  PubChem Substance ID 24845563

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Properties

Related Categories Chelation/Complexation Compounds, Chemical Synthesis, EDTA Derivatives, Synthetic Reagents
assay   ≥97.0% (KT)

Description

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
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Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
2

Documents

Certificate of Analysis

Protocols & Articles

Peer-Reviewed Papers

References

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Merck 14,3517

Beil. 4,IV,2451

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