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03780 Sigma-Aldrich

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid

≥98.0% (T)

Synonym: EGTA, Egtazic acid, Ethylene-bis(oxyethylenenitrilo)tetraacetic acid, Glycol ether diamine tetraacetic acid

  • CAS Number 67-42-5

  • Linear Formula [-CH2OCH2CH2N(CH2CO2H)2]2

  • Molecular Weight 380.35

  •  Beilstein Registry Number 1717370

  •  EC Number 200-651-2

  •  MDL number MFCD00004291

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Properties

Related Categories Biochemicals and Reagents, Chelation/Complexation Compounds, Chelators, Chemical Synthesis, EDTA Derivatives,
InChI Key   DEFVIWRASFVYLL-UHFFFAOYSA-N
assay   ≥98.0% (T)
mp   241 °C (dec.)(lit.)
  ~250 °C (dec.)

Description

Application

A chelating agent useful for the determination of calcium in the presence of magnesium.

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid also referred to as EGTA or Egtazic acid is a chelating agent that facilitates the determination of calcium in the presence of magnesium. EGTA has also been used for preparing the cytoskeleton buffer used in whole-mount electron microscopy of the cytoskeleton.

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Biochem/physiol Actions

EGTA is an aminopolycarboxylic acid that inhibits the calcium-activated potassium conductance during the hyperpolarization in hippocampal CA3 pyramidal cells. EGTA induces apoptosis in PC12 cells and stimulates (Ca2+-Mg2+)-ATPase in rat liver plasma membranes.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
AH3760000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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