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05646 Sigma-Aldrich

Alcohol Dehydrogenase from equine liver

crystalline suspension in 20 mM potassium phosphate buffer, ~2 U/mg protein (~10 mg/ml)

Synonym: ADH, Alcohol Dehydrogenase from horse liver, Alcohol:NAD+ oxidoreductase, HLADH

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Description

Other Notes

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Same product — same quality — now Sigma-Aldrich brand

Unit Definition

1 U corresponds to the amount of enzyme which oxidizes 1 μmol ethanol per minute at pH 8.8 and 25 °C

Application

Alcohol dehydrogenase breaks down potentially toxic alcohols and is involved in the biosynthesis of various metabolites. Alcohol dehydrogenase is used to study its role in alcoholism and cancer . Alcohol dehydrogenase, from horse liver, has been used to prepare proteins in order to study the specificity of retinol dehydrogenases .

Biochem/physiol Actions

Alcohol dehydrogenase facilitates the interconversion between alcohols and aldehydes or ketones. In yeast and bacteria, alcohol dehydrogenase is involved in fermentation. Genetic mutations in the alcohol dehydrogenase gene cluster many increase the risk of developing gastric cancer .

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

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Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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