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08570 Sigma-Aldrich

2-Amino-2-methyl-1,3-propanediol

≥97.0% (GC)

Synonym: AMPD, Ammediol

  • CAS Number 115-69-5

  • Linear Formula (HOCH2)2C(NH2)CH3

  • Molecular Weight 105.14

  •  Beilstein Registry Number 635708

  •  EC Number 204-100-7

  •  MDL number MFCD00004678

  •  PubChem Substance ID 24846197

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Properties

Related Categories Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds More...
vapor density   3.63 (vs air)
vapor pressure   ~10 mmHg ( 152 °C)
InChI Key   UXFQFBNBSPQBJW-UHFFFAOYSA-N
assay   ≥97.0% (GC)
loss   ~1% loss on drying
useful pH range   7.8 - 9.7
pKa (25 °C)   8.8
bp   151 °C/10 mmHg(lit.)
mp   100-110 °C(lit.)
  100-110 °C
solubility   water: soluble105.1 g/L

Description

Application

Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.

2-Amino-2-methyl-1,3-propanediol has been used as a spacer in isotachophoresis of proteins.It has also been used as a buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Additionally, it has been used as a buffer for the determination of alkaline phosphatase activity.

Other Notes

Same product — same quality — now Sigma-Aldrich brand

General description

2-Amino-2-methyl-1,3-propanediol also referred to as AMPD or Ammediol is a biological buffer. It is used in the resolving phase of the gel and stabilizes the pH as well as assists in separating the proteins with wide range of molecular sizes (10 kDa to over 220 kDa) using unusually low-concentrated gels.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3259PSN1 8 / PGII
WGK Germany 
1
RTECS 
TY2975000
Protocols & Articles
Peer-Reviewed Papers
15

References

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