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09581 Sigma-Aldrich

L-Glutamic acid

tested according to Ph.Eur.

Synonym: (S)-2-Aminopentanedioic acid, Acidum glutamicum, Glu

  • CAS Number 56-86-0

  • Linear Formula HO2CCH2CH2CH(NH2)CO2H

  • Molecular Weight 147.13

  •  Beilstein Registry Number 1723801

  •  EC Number 200-293-7

  •  MDL number MFCD00002634

  •  PubChem Substance ID 329748776

  •  eCl@ss 32160406

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Properties

Related Categories Amino Acids, Analytical/Chromatography, Core Bioreagents, Pharmacopoeia, Pharmacopoeia A-Z,
InChI Key   WHUUTDBJXJRKMK-VKHMYHEASA-N
assay   99.9%
pharmacopeia   testing conforms to Pharmacopeia
mp   205 °C (dec.)(lit.)
solubility   water: soluble 8.64 g/L at 25 °C
Gene Information   human ... CCR2(1231), GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK5(2901), GRIN2B(2904), GRM2(2912), SLC1A1(6505), SLC1A2(6506)
rat ... Gria1(50592), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grm1(24414), Grm2(24415), Grm3(24416), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672), Slc1a2(29482)

Description

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

L-Glutamic acid along with l-Lysine is used for preparation of bifunctional DTPA-like ligands. L-glutamic acid can stimulate the spontaneous release of [3H] dopamine ( [3H] DA).

Application

L-Glutamic acid is an excitatory neurotransmitter used as a test compound for studying the impact of excitatory amino acids and their antagonists on membrane and action potentials of cat caudate neurones.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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