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11332 Sigma-Aldrich

Atropine sulfate salt monohydrate

tested according to Ph.Eur.

Synonym: α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, Atropini sulfas, Tropine tropate

  • CAS Number 5908-99-6

  • Linear Formula (C17H23NO3)2 · H2SO4 · H2O

  • Molecular Weight 694.83

  •  Beilstein Registry Number 6109275

  •  EC Number 200-235-0

  •  MDL number MFCD00074815

  •  PubChem Substance ID 24846875

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Properties

Related Categories Analytical/Chromatography, Pharmacopoeia, Pharmacopoeia A-Z More...
InChI Key   JPKKQJKQTPNWTR-CHYDPLAESA-N
pharmacopeia   testing conforms to Pharmacopeia
mp   189-192 °C (A)(lit.)
solubility   water: soluble2500 g/L at 4 °C

Description

Biochem/physiol Actions

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Atropine sulfate salt monohydrate is a competitive nonselective antagonist of central and peripheral muscarinic acetylcholine receptors. Atropine is a cholinergic receptor antagonist isolated from Atropa belladona L., Datura stramonium L. and other plants of the solanaceae family. It blocks the ion currents mediated by neuronal nicotinic acetylcholine receptors. Further, it blocks the acetylcholine (ACh)-induced relaxations in human pulmonary veins.

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Application

Atropine sulfate salt monohydrate has been used for anaesthetizing mice for intranasal administration of ropinirole or 7-OH-DPAT.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1544PSN2 6.1 / PGII
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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