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12070 Sigma-Aldrich

Benzamide

purum, ≥98.0% (HPLC)

Synonym: Benzoic acid amide

  • CAS Number 55-21-0

  • Linear Formula C6H5CONH2

  • Molecular Weight 121.14

  •  Beilstein Registry Number 385876

  •  EC Number 200-227-7

  •  MDL number MFCD00007968

  •  PubChem Substance ID 329749611

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Properties

Related Categories Amides, Building Blocks, C2 to C7, Carbonyl Compounds, Chemical Synthesis,
InChI Key   KXDAEFPNCMNJSK-UHFFFAOYSA-N
grade   purum
assay   ≥98.0% (HPLC)
mp   125-128 °C(lit.)
  125-128 °C
solubility   methanol: soluble 1 g/10 mL clear, colorless to faintly yellow

Description

Biochem/physiol Actions

Inhibits poly(ADP-ribose) polymerase (PARP).

Benzamide is a specific inhibitor of poly(ADP-ribose)polymerase. It prevents glutamate- and methamphetamine-induced neurotoxicity in vitro in C57B1/6N mouse.

Application

Benzamide was used to study the effect of inhibitors of endonuclease and poly(ADP ribose) polymerase on anti-Fas monoclonal antibody treated Jurkat cells.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
CU8700000
Flash Point(F) 
356 °F
Flash Point(C) 
180 °C

Documents

Certificate of Analysis

Protocols & Articles

Articles

HPLC Analysis of Polar Compounds on Ascentis® Express RP-Amide Particles

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Polar Compounds on Ascentis® Express RP-Amide Particles
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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Product #

Description

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135828 Benzamide, 99%

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