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  • 12809 - O-(Benzotriazol-1-yl)-N,N,N′,N′-bis(tetramethylene)uronium hexafluorophosphate

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12809 Sigma-Aldrich

O-(Benzotriazol-1-yl)-N,N,N′,N′-bis(tetramethylene)uronium hexafluorophosphate

≥98.0%

Synonym: (Benzotriazol-1-yloxy)dipyrrolidinocarbenium hexafluorophosphate, HBPyU

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling,
InChI Key   XKTRAGMCMJYRRN-UHFFFAOYSA-N
assay   ≥98.0%
mp   176 °C (dec.)(lit.)
solubility   acetonitrile: soluble0.1 g/mL, clear
storage temp.   2-8°C

Description

Other Notes

Recent studies show that crystal and solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Non-hygroscopic, extremely reactive reagent for peptide coupling giving low racemization. Reaction by-products are non-cytotoxic

Same product — same quality — now Sigma-Aldrich brand

Packaging

5 g in glass bottle

Application

Catalyst for synthesis of dyes

Reagent for peptide coupling

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

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Peer-Reviewed Papers
15

References

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