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14340 Sigma-Aldrich

(+)-Bicuculline

≥97.0% (TLC)

  • CAS Number 485-49-4

  • Empirical Formula (Hill Notation) C20H17NO6

  • Molecular Weight 367.35

  •  Beilstein Registry Number 98786

  •  EC Number 207-619-7

  •  MDL number MFCD00005006

  •  PubChem Substance ID 329750455

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Properties

Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology
InChI Key   IYGYMKDQCDOMRE-ZWKOTPCHSA-N
assay   ≥97.0% (TLC)
optical activity   [α]20/D +126±6°, c = 1% in chloroform
mp   193-197 °C
Gene Information   rat ... Gabra2(29706)

Description

Biochem/physiol Actions

(+)-Bicuculline is a GABAA receptor antagonist.

(+)-Bicuculline is a GABAA receptor antagonist, which acts as a competitive inhibitor of GABA liganding binding to the receptor.

Other Notes

GABA antagonist

Features and Benefits

This compound is featured on the GABAC Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
LV0909840

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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