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14400 Sigma-Aldrich

Biotin

≥99.0% (T)

Synonym: D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

  • CAS Number 58-85-5

  • Empirical Formula (Hill Notation) C10H16N2O3S

  • Molecular Weight 244.31

  •  Beilstein Registry Number 86838

  •  EC Number 200-399-3

  •  MDL number MFCD00005541

  •  PubChem Substance ID 329750287

  •  eCl@ss 34058011

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Properties

Related Categories Allium sativum (Garlic), Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C,
InChI Key   YBJHBAHKTGYVGT-ZKWXMUAHSA-N
assay   ≥99.0% (T)
optical activity   [α]20/D +91±2°, c = 1% in 0.1 M NaOH
ign. residue   ≤0.1% (as SO4)
loss   ≤0.5% loss on drying
mp   229-234 °C
  231-233 °C(lit.)
solubility   alcohol: soluble80mg/100 ml at 25 °C
  water: soluble22mg/100 ml at 25 °C
  0.1 M NaOH: soluble10 mg/mL at 25 °C, clear, colorless
  H2O: very soluble
  organic solvents: insoluble
cation traces   Ca: ≤50 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤10 mg/kg
  K: ≤50 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤500 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg

Description

Other Notes

Reviews; Avidin-Biotin technology;

Application

Biotin has been used for testing the functionality of the Avidin-displaying phages. The product has also been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

Biochem/physiol Actions

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Price and Availability


Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
XJ9088200
Protocols & Articles
Peer-Reviewed Papers
15

References

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