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14690 Sigma-Aldrich

Bis(cyclohexanone)oxaldihydrazone

for spectrophotometric det. of Cu, ≥99.0%

Synonym: Cuprizon, Cuprizone, Oxalic acid bis(cyclohexylidenehydrazide)

  • CAS Number 370-81-0

  • Empirical Formula (Hill Notation) C14H22N4O2

  • Molecular Weight 278.35

  •  Beilstein Registry Number 2388004

  •  EC Number 206-729-2

  •  MDL number MFCD00001659

  •  PubChem Substance ID 24848801

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Spectroscopy, UV/Vis Reagents, UV/Visible (UV/VIS) Spectroscopy More...
InChI Key   DSRJIHMZAQEUJV-UHFFFAOYSA-N
assay   ≥99.0% (N)
  ≥99.0%
quality   for spectrophotometric det. of Cu
mp   210-214 °C(lit.)
  210-214 °C

Description

Other Notes

For the spectrophotometric determination of Cu(II)

In the presence of a copper salt, this ligand catalyzes Ullmann-type C-N bond forming reactions under mild, aqueous conditions.

Same product — same quality — now Sigma-Aldrich brand

Application

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.

General description

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.

Price and Availability

Suggested Laboratory Gloves


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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
RO2520000
Protocols & Articles
Peer-Reviewed Papers
15

References

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