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15527 Sigma-Aldrich

Glycine

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

Synonym: Aminoacetic acid, Aminoethanoic acid, Glycocoll

  • CAS Number 56-40-6

  • Linear Formula NH2CH2COOH

  • Molecular Weight 75.07

  •  Beilstein Registry Number 635782

  •  EC Number 200-272-2

  •  MDL number MFCD00008131

  •  PubChem Substance ID 57647473

  •  eCl@ss 32160406

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Properties

Related Categories Amino Acids, Core Bioreagents, Research Essentials More...
InChI Key   DHMQDGOQFOQNFH-UHFFFAOYSA-N
assay   99-101% (based on anhydrous substance)
quality   meets analytical specification of Ph. Eur., BP, USP
impurities   hydrolyzable substances, complies
  organic volatile impurities, complies (GC)
  residual solvents, complies
  ≤0.001% heavy metals (as Pb)
  ≤0.5% other ninhydrin-positive substances
ign. residue   ≤0.1% (as SO4)
loss   ≤0.2% loss on drying, 105 °C, 2 h
pH   5.9-6.4 (20 °C, 5%)
pKa (25 °C)   2.35
mp   240 °C (dec.)(lit.)
solubility   H2O: soluble25 gm in 100 ml at 25 degrees c
  H2O: soluble39.1 gm in 100 ml at 50 degrees c
  alcohol: soluble0.06 gm in 100 gm (Absolute)
  pyridine: soluble164 parts
  alcohol: very slightly soluble
  diethyl ether: very slightly soluble
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤50 mg/kg
suitability   complies for appearance of solution
  complies for reaction against H2SO4
  in accordance for identity (IR)
Gene Information   rat ... Grin2a(24409)

Description

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

Application

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
MB7600000
Protocols & Articles
Peer-Reviewed Papers
15

References

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