• USA Home
  • 158534 - Trifluoromethanesulfonic acid

EMAIL THIS PAGE TO A FRIEND
158534 Sigma-Aldrich

Trifluoromethanesulfonic acid

reagent grade, 98%

Synonym: Triflic acid

Purchase

Properties

Related Categories Acids, Acids & Bases, Chemical Synthesis, Organic Acids, Synthetic Reagents More...
grade   reagent grade
vapor density   5.2 (vs air)
vapor pressure   8 mmHg ( 25 °C)
InChI Key   ITMCEJHCFYSIIV-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.327(lit.)
bp   162 °C(lit.)
density   1.696 g/mL at 25 °C(lit.)

Description

Application

Deglycosylation agent

Trifluoromethanesulfonic acid is a versatile reagent, employed as catalyst for the following studies:
• Friedel-Crafts acylation of aromatic compounds with methyl benzoate.
• Addition reaction of dialkyl disulfides to terminal alkynes.
• Synthesis of a single cyclic tetrasiloxane containing propylammonium trifluoromethanesulfonate and methyl side-chain groups (Am-CyTS).
• Preparation of starting reagents for the synthesis of fluorinated 2,5-substituted 1-ethyl-1H-benzimidazole derivatives.
• Synthesis of aryl triflates, the lactonization of alkenoic acids, and the formation of E-alkenes.

Packaging

10, 50, 100 g in ampule

General description

Trifluoromethanesulfonic acid is the strongest monoprotic organic acid. It has been synthesized by the oxidation of bis(trifluoromethylthio)mercury with aqueous hydrogen peroxide. It undergoes complete dissociation in basic solvents such as dimethyl sulfoxide, dimethylacetamide and dimethylformamide. Its dissociation in non-aqueous solvents has been studied by conductometry. On mixing trifluoromethanesulfonic acid with HNO3, it forms nitronium trifluoromethane sulfonate, which is an excellent nitrating reagent.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3265 8 / PGII
WGK Germany 
1

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Friedel–Crafts Acylation

The Friedel–Crafts acylation is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst. This reaction proceeds via electrophilic aromatic substitution to form m...
Keywords: Acylations, Catalysis, Electrophilic aromatic substitution, Microwave synthesis, Substitutions

Related Content

Molarity Calculator and Normality Calculator for Acids and Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution.  To...

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

accessory

Product #

Description

Add to Cart

Z693847 Scienceware® Break-Safe ampule opener

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?