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22642 Sigma-Aldrich

Quinine hemisulfate salt monohydrate

tested according to Ph.Eur.

Synonym: Chinini sulfas, Quinine sulfate (2:1) (salt) dihydrate

  • CAS Number 207671-44-1

  • Empirical Formula (Hill Notation) C20H24N2O2 · 0.5H2O4S · H2O

  • Molecular Weight 391.47

  •  Beilstein Registry Number 6113937

  •  MDL number MFCD00150790

  •  PubChem Substance ID 329752331

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Description

Application

Quinine hemisulfate salt monohydrate has been used as a tastant for testing the saccharin and quinine consumption in wild-type or knock-in mice. It has been used for studying the toxicity of heme (FP)-complexes.

Biochem/physiol Actions

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Quinine hemisulfate is an alkaloid originally isolated from the Cinchona family of South American trees. It inhibits mitochondrial ATP-regulated potassium channel and posssess antimalarial, anticholinergic, antihypertensive and hypoglycemic properties.

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Laboratory Gloves

All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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