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22642 Sigma-Aldrich

Quinine hemisulfate salt monohydrate

tested according to Ph.Eur.

Synonym: Chinini sulfas, Quinine sulfate (2:1) (salt) dihydrate

  • CAS Number 207671-44-1

  • Empirical Formula (Hill Notation) C20H24N2O2 · 0.5H2O4S · H2O

  • Molecular Weight 391.47

  •  Beilstein Registry Number 6113937

  •  MDL number MFCD00150790

  •  PubChem Substance ID 24853567

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Description

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Application

Quinine hemisulfate salt monohydrate has been used as a tastant for testing the saccharin and quinine consumption in wild-type or knock-in mice. It has been used for studying the toxicity of heme (FP)-complexes.

Biochem/physiol Actions

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Quinine hemisulfate is an alkaloid originally isolated from the Cinchona family of South American trees. It inhibits mitochondrial ATP-regulated potassium channel and posssess antimalarial, anticholinergic, antihypertensive and hypoglycemic properties.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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