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227056 Sigma-Aldrich

N,N-Dimethylformamide

anhydrous, 99.8%

Synonym: DMF, NSC 5356

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Properties

Related Categories Anhydrous, Anhydrous Solvents, Products, Returnable Containers, Solvent Bottles,
grade   anhydrous
vapor density   2.5 (vs air)
vapor pressure   2.7 mmHg ( 20 °C)
assay   99.8%
autoignition temp.   833 °F
expl. lim.   15.2 %
impurities   <0.005% water
evapn. residue   <0.0005%
refractive index   n20/D 1.430(lit.)
bp   153 °C(lit.)
mp   −61 °C(lit.)
density   0.944 g/mL(lit.)

Description

Application

Solvent for many hydrophobic organic compounds.

Packaging

1, 6×1, 2, 4×2 L in Sure/Seal™

View returnable container options.

100, 12×100 mL in Sure/Seal™

18, 200 L in Pure-Pac™ 1

Price and Availability

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
T
Risk Statements (Europe) 
Safety Statements (Europe) 
53-45
RIDADR 
UN 2265 3 / PGIII
WGK Germany 
2
RTECS 
LQ2100000
Flash Point(F) 
136.4 °F
Flash Point(C) 
58 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in N,N-Dimethyl formamide Using Karl Fischer Titration

N,N-Dimethyl formamide is occasionally described as a solvent used in the working medium of the KF titration to aid solubility of certain samples, for example in the pharmacopoeia. In the presence of...
Keywords: Solvents, Titrations

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Peer-Reviewed Papers

References

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A second-order nonlinear optical material with a hydrated homochiral helix obtained via spontaneous symmetric breaking crystallization from an achiral ligand. Yang Q, Chen Z, Hu J, et al. Chem. Commun. (Camb.) 49(34), 3585-7, (2013)

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Highly stable trypsin-aggregate coatings on polymer nanofibers for repeated protein digestion. Kim BC Proteomics 9(7), 1893-900, (2009)

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Effect of acute exposure of N,N-dimethylformamide, an industrial solvent on lipid peroxidation and antioxidants in liver and kidney of rats. Jyothi K, Kalyani D, and Nachiappan V Indian J. Biochem. Biophys. 49(4), 279-84, (2012)

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Synthesis of bis-acyclonucleoside analogues bearing benzothienyl-1,2,4-Triazol-3-Yl-disulfide under conventional and microwave methods. Aouad MR, Rezki N, Messali M, et al. Nucleosides Nucleotides Nucleic Acids 32(1), 28-41, (2013)

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Merck 14,3243

Beil. 4,IV,171

Fieser 1,273 / Fieser 1,278 / Fieser 2,153 / Fieser 3,115 / Fieser 4,184 / Fieser 5,247 / Fieser 7,124 / Fieser 8,189 / Fieser 9,182 / Fieser 11,198 / Fieser 12,203 / Fieser 14,148 / Fieser 16,144

Aldrich MSDS 1, 770:A / Corp MSDS 1 (1), 1374:A / FT-IR 2 (1), 1278:A / FT-IR 1 (1), 758:D / FT-NMR 1 (1), 1239:C / IR-Spectra (3), 443:E / IR-Spectra (2), 392:D / IR-Spectra (3), 443:D / NMR-Reference 2 (1), 639:A / RegBook 1 (1), 891:A / Sax 6, 1163 / Sigma FT-IR 1 (2), 500:D / Structure Index 1, 136:D:7 / Vapor Phase 3, 781:B

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