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23185 Sigma-Aldrich

Fmoc chloride

purum, ≥98.0% (HPLC)

Synonym: 9-Fluorenylmethoxycarbonyl chloride, 9-Fluorenylmethyl chloroformate, Fmoc-Cl

  • CAS Number 28920-43-6

  • Empirical Formula (Hill Notation) C15H11ClO2

  • Molecular Weight 258.70

  •  Beilstein Registry Number 2279177

  •  EC Number 249-313-6

  •  MDL number MFCD00001138

  •  PubChem Substance ID 329752392

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Description

Application

Reagent for derivatizing amino acids for HPLC amino acid analysis and for preparing N-Fmoc amino acids for solid-phase peptide synthesis.

Other Notes

For the introduction of the 9-fluorenylmethoxycarbonyl (Fmoc) amino-protecting group, which is stable towards acids and catalytic hydrogenation, but readily cleaved under mildly basic non-hydrolytic conditions; Use of the Fmoc-group for the protection of hydroxy groups; protection of amino groups in nucleotides

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
3
RTECS 
LQ6250000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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160512 Fmoc chloride, 97%

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