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242284 Sigma-Aldrich

Aniline

ACS reagent, ≥99.5%

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Properties

grade   ACS reagent
vapor density   3.22 (185 °C, vs air)
vapor pressure   0.7 mmHg ( 25 °C)
assay   ≥99.5%
autoignition temp.   1139 °F
expl. lim.   11 %
impurities   Hydrocarbons, passes test
  Nitrobenzene, passes test (lim. ~0.001%)
  ≤0.01% chlorobenzene
ign. residue   ≤0.005%
color   APHA: ≤250
refractive index   n20/D 1.586(lit.)
bp   184 °C(lit.)
mp   −6 °C(lit.)
solubility   water: soluble
density   1.022 g/mL at 25 °C(lit.)

Description

Biochem/physiol Actions

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

Packaging

5, 100, 4×100, 500 mL in glass bottle

Physical properties

Material darkens in storage to reddish-brown with no loss in purity.

Price and Availability

Safety & Documentation

Safety Information

Signal word 
Danger
Precautionary statements 
Target organs 
Blood
RIDADR 
UN 1547 6.1 / PGII
WGK Germany 
3
RTECS 
BW6650000
Flash Point(F) 
158 °F
Flash Point(C) 
70 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in Aniline Using Karl Fischer Titration

Nitrogen compounds, acid amides and weakly basic amines (heterocyclenes) give no problems. They can be titrated according to the standard procedures. Strongly basic amines alter the pH value and must...
Keywords: Pharmaceutical, Solvents, Titrations

Determination of Water Content in Aniline Using Karl Fischer Titration

Nitrogen compounds, acid amides and weakly basic amines (heterocyclenes) give no problems. They can be titrated according to the standard procedures. Strongly basic amines alter the pH value and must...
Keywords: Pharmaceutical, Solvents, Titrations

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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