251917 Sigma-Aldrich

Sulfanilic acid

ACS reagent, 99%

Synonym: 4-Aminobenzenesulfonic acid, Aniline-4-sulfonic acid

  • CAS Number 121-57-3

  • Linear Formula 4-(H2N)C6H4SO3H

  • Molecular Weight 173.19

  •  Beilstein Registry Number 908765

  •  EC Number 204-482-5

  •  MDL number MFCD00007886

  •  PubChem Substance ID 24855168



Related Categories Acids, Acids & Bases, Building Blocks, Chemical Synthesis, Organic Acids,
grade   ACS reagent
assay   98.0-102.0% (ACS specification)
ign. residue   ≤0.01%
mp   >300 °C(lit.)
anion traces   chloride (Cl-): ≤0.002%
  nitrite (NO2-): ≤0.5 ppm
  sulfate (SO42-): ≤0.01%



25, 100, 500 g in poly bottle

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Sulfanilic acid

puriss. p.a., ≥99.0% (T)

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Safety Information

GHS07  GHS07
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Peer-Reviewed Papers


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Biodegradation of 4-aminobenzenesulfonate by a novel Pannonibacter sp. W1 isolated from activated sludge. Wang YQ, Zhang JS, Zhou JT, et al. J. Hazard. Mater. 169(1-3), 1163-7, (2009)


Electrochemical incineration of sulfanilic acid at a boron-doped diamond anode. El-Ghenymy A, Arias C, Cabot PL, et al. Chemosphere 87(10), 1126-33, (2012)


Degradation and detoxification of acid orange 52 by Pseudomonas putida mt-2: a laboratory study. Mansour HB, Ghedira K, Barillier D, et al. Environ. Sci. Pollut. Res. Int. 18(9), 1527-35, (2011)


[Kinetics and mechanism of 4-aminobenzenesulphonate biodegradation]. Wang YQ, Zhang JS, Zhou JT, et al. Huan Jing Ke Xue 30(7), 2136-41, (2009)


[Isolation and identification of a 4-aminobenzenesulphonate biodegrading strain and its degradation characteristics]. Wang YQ, Zhang JS, Zhou JT, et al. Huan Jing Ke Xue 30(4), 1193-8, (2009)


Copper-catalyzed synthesis of substituted benzothiazoles via condensation of 2-aminobenzenethiols with nitriles. Sun Y, Jiang H, Wu W, et al. Org. Lett. 15(7), 1598-601, (2013)


Aptamer-mediated surface-enhanced Raman spectroscopy intensity amplification. Kim NH, Lee SJ, and Moskovits M Nano Lett. 10(10), 4181-5, (2010)


Electrochemical biosensor for detection of BCR/ABL fusion gene using locked nucleic acids on 4-aminobenzenesulfonic acid-modified glassy carbon electrode. Chen J, Zhang J, Wang K, et al. Anal. Chem. 80(21), 8028-34, (2008)


Efficient 2-aryl benzothiazole formation from aryl ketones and 2-aminobenzenethiols under metal-free conditions. Liao Y, Qi H, Chen S, et al. Org. Lett. 14(23), 6004-7, (2012)


Reversible tuning of SERS hot spots with aptamers. Kim NH, Lee SJ, and Moskovits M Adv. Mater. 23(36), 4152-6, (2011)


Sensitive voltammetric determination of tyrosine using multi-walled carbon nanotubes/4-aminobenzeresulfonic acid film-coated glassy carbon electrode. Huang KJ, Luo DF, Xie WZ, et al. Colloids Surf. B Biointerfaces 61(2), 176-81, (2008)


Surface-enhanced Raman scattering of 4-aminobenzenethiol in Ag sol: relative intensity of a1- and b2-type bands invariant against aggregation of Ag nanoparticles. Kim K, Yoon JK, Lee HB, et al. Langmuir 27(8), 4526-31, (2011)


Effect of Ag and Au nanoparticles on the SERS of 4-aminobenzenethiol assembled on powdered copper. Kim K and Lee HS J. Phys. Chem. B 109(40), 18929-34, (2005)


Biodegradation of 4-aminobenzenesulfonate by Ralstonia sp. PBA and Hydrogenophaga sp. PBC isolated from textile wastewater treatment plant. Gan HM, Shahir S, Ibrahim Z, et al. Chemosphere 82(4), 507-13, (2011)


Mineralization of 4-aminobenzenesulfonate (4-ABS) by Agrobacterium sp. strain PNS-1. Singh P, Birkeland NK, Iyengar L, et al. Biodegradation 17(6), 495-502, (2006)


Free-surface microfluidic control of surface-enhanced Raman spectroscopy for the optimized detection of airborne molecules. Piorek BD, Lee SJ, Santiago JG, et al. Proc. Natl. Acad. Sci. U. S. A. 104(48), 18898-901, (2007)


Application of a novel bacterial consortium for mineralization of sulphonated aromatic amines. Barsing P, Tiwari A, Joshi T, et al. Bioresour. Technol. 102(2), 765-71, (2011)


Enhanced biodegradation of 4-aminobenzenesulfonate in membrane bioreactor by Pannonibacter sp. W1. Zhang J, Wang Y, Zhou JT, et al. Water Sci. Technol. 63(11), 2752-8, (2011)


Cloning and functional analysis of the genes coding for 4-aminobenzenesulfonate 3,4-dioxygenase from Hydrogenophaga sp. PBC. Gan HM, Shahir S, and Yahya A Microbiology 158(Pt 8), 1933-41, (2012)


Evaporation-controlled chemical enhancement of SERS using a soft polymer substrate. Kim NJ, Lin M, Hu Z, et al. Chem. Commun. (Camb.) (41), 6246-8, (2009)


Genome sequence of Hydrogenophaga sp. strain PBC, a 4-aminobenzenesulfonate-degrading bacterium. Gan HM, Chew TH, Tay YL, et al. J. Bacteriol. 194(17), 4759-60, (2012)


Surface-enhanced Raman scattering characteristics of nanogaps formed by a flat Ag substrate and spherical Pt nanoparticles. Kim K, Lee HB, and Shin KS Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 100, 10-4, (2013)


Raman scattering of 4-aminobenzenethiol sandwiched between Ag nanoparticle and macroscopically smooth Au substrate: effects of size of Ag nanoparticles and the excitation wavelength. Kim K, Choi JY, Lee HB, et al. J. Chem. Phys. 135(12), 124705, (2011)


Genome sequence of Ralstonia sp. strain PBA, a bacterium involved in the biodegradation of 4-aminobenzenesulfonate. Gan HM, Chew TH, Tay YL, et al. J. Bacteriol. 194(18), 5139-40, (2012)


Identification of genes involved in the 4-aminobenzenesulfonate degradation pathway of Hydrogenophaga sp. PBC via transposon mutagenesis. Gan HM, Ibrahim Z, Shahir S, et al. FEMS Microbiol. Lett. 318(2), 108-14, (2011)


Mutagenicity and genotoxicity of acid yellow 17 and its biodegradation products. Mansour HB, Mosrati R, Corroler D, et al. Drug Chem. Toxicol. 32(3), 222-9, (2009)


Merck 14,8926

Beil. 14,IV,2655

Corp MSDS 1 (2), 3197:B / FT-IR 2 (2), 3227:B / FT-IR 1 (2), 493:D / FT-NMR 1 (2), 1595:A / IR-Spectra (2), 1006:D / IR-Spectra (3), 1155:B / RegBook 1 (2), 2197:B / Structure Index 1, 345:C:1

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