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26210 Sigma-Aldrich

3-Chloropropionyl chloride

purum, ≥98.0% (GC)

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Properties

Related Categories Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks More...
InChI Key   INUNLMUAPJVRME-UHFFFAOYSA-N
grade   purum
assay   ≥98.0% (GC)
refractive index   n20/D 1.457(lit.)
  n20/D 1.457
bp   143-145 °C(lit.)
density   1.324 g/mL at 20 °C
  1.33 g/mL at 25 °C(lit.)

Description

Application

3-Chloropropionyl chloride has been used in:
• microwave-promoted liquid-phase synthesis of 3,5-disubstituted 2-thioxotetrahydropyrimidin-4-ones
• preparation of hydrophilic and macroporous polymer resins modified with isothiocyanate groups
• synthesis of diethylaminopropionamido-hydroxy-anthraquinones, which are potential anticancer agents

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Reacts violently with water.
RIDADR 
UN 3390 8(6.1) / PGI
WGK Germany 
1
Flash Point(F) 
145.4 °F
Flash Point(C) 
63 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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