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26980 Sigma-Aldrich

Choline chloride

≥97.0% (AT)

Synonym: (2-Hydroxyethyl)trimethylammonium chloride

  • CAS Number 67-48-1

  • Linear Formula (CH3)3N(Cl)CH2CH2OH

  • Molecular Weight 139.62

  •  Beilstein Registry Number 3563126

  •  EC Number 200-655-4

  •  MDL number MFCD00011721

  •  PubChem Substance ID 329752892

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Properties

Related Categories Ammonium Salts, Chemical Synthesis, Phase Transfer Catalysts, Synthetic Reagents
InChI Key   SGMZJAMFUVOLNK-UHFFFAOYSA-M
assay   ≥97.0% (AT)
mp   302-305 °C (dec.)(lit.)

Description

Substrates

Choline acetyltransferase substrate

Biochem/physiol Actions

The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .

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Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
1
RTECS 
KH2975000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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