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270970 Sigma-Aldrich

Pyridine

anhydrous, 99.8%

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Properties

Related Categories Anhydrous, Anhydrous Solvents, Products, Pyridine, Returnable Containers,
grade   anhydrous
vapor density   2.72 (vs air)
vapor pressure   10 mmHg ( 13.2 °C)
  20 mmHg ( 25 °C)
assay   99.8%
autoignition temp.   899 °F
expl. lim.   12.4 %
impurities   <0.003% water
  <0.005% water (100 mL pkg)
evapn. residue   <0.0005%
refractive index   n20/D 1.509(lit.)
bp   115 °C(lit.)
mp   −42 °C(lit.)
density   0.978 g/mL at 25 °C(lit.)

Description

Packaging

1, 6×1, 2, 4×2 L in Sure/Seal™

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200 L in Pure-Pac™ 1

4×25, 100, 12×100 mL in Sure/Seal™

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
Risk Statements (Europe) 
Safety Statements (Europe) 
26-28
RIDADR 
UN 1282 3 / PGII
WGK Germany 
2
RTECS 
UR8400000
Flash Point(F) 
62.6 °F
Flash Point(C) 
17 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in Pyridine Using Karl Fischer Titration

Nitrogen compounds, acid amides and weakly basic amines (heterocyclenes) give no problems. They can be titrated according to the standard procedures. Strongly basic amines alter the pH value and must...
Keywords: Titrations

Peer-Reviewed Papers

References

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Modular pyridine synthesis from oximes and enals through synergistic copper/iminium catalysis. Wei Y and Yoshikai N J. Am. Chem. Soc. 135(10), 3756-9, (2013)

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Total syntheses of complanadines A and B. Zhao L, Tsukano C, Kwon E, et al. Angew. Chem. Int. Ed. Engl. 52(6), 1722-5, (2013)

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Synthesis and characterization of hexa-coordinated Sn(IV) complexes of meso-aryl dipyrrins. Sharma R, Ghosh A, Wolfram B, et al. Dalton Trans. 42(16), 5627-30, (2013)

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Catalytic wet peroxidation of pyridine bearing wastewater by cerium supported SBA-15. Subbaramaiah V, Srivastava VC, and Mall ID J. Hazard. Mater. 248-249, 355-63, (2013)

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Rapid identification of ligand-binding sites by using an assignment-free NMR approach. Kodama Y, Takeuchi K, Shimba N, et al. J. Med. Chem. 56(22), 9342-50, (2013)

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Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine. Paul M O'Neill et al J. Med. Chem. 52, 1828-44, (2009)

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Photogenerated avenues in macromolecules containing Re(I), Ru(II), Os(II), and Ir(III) metal complexes of pyridine-based ligands. Happ B, Winter A, Hager MD, et al. Chem. Soc. Rev. 41(6), 2222-55, (2012)

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Synthesis and application of ionic liquid matrices (ILMs) for effective pathogenic bacteria analysis in matrix assisted laser desorption/ionization (MALDI-MS). Abdelhamid HN, Gopal J, and Wu HF Anal. Chim. Acta 767, 104-11, (2013)

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Is comprehensive analysis of potentially relevant migrants from recycled paperboard into foods feasible? Biedermann M and Grob K J. Chromatogr. A 1272, 106-15, (2013)

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Modular synthesis of alkyne-substituted ruthenium polypyridyl complexes suitable for "click" coupling. Gerken JB, Rigsby ML, Ruther RE, et al. Inorg. Chem. 52(6), 2796-8, (2013)

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Hetero diels-alder chemistry for the functionalization of single-walled carbon nanotubes with cyclopentadienyl end-capped polymer strands. Zydziak N, Preuss CM, Winkler V, et al. Macromol. Rapid Commun. 34(8), 672-80, (2013)

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Iron coordination chemistry with new ligands containing triazole and pyridine moieties. Comparison of the coordination ability of the N-donors. Ségaud N, Rebilly JN, Sénéchal-David K, et al. Inorg. Chem. 52(2), 691-700, (2013)

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Bioconjugation with stable luminescent lanthanide(III) chelates comprising pyridine subunits. Hovinen J and Guy PM Bioconjug. Chem. 20(3), 404-21, (2009)

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Selective recognition of sulphate in a Cu(II) assisted 1D polymer of a simple pentafluorophenyl substituted pyridyl-urea via second sphere coordination. Akhuli B and Ghosh P Dalton Trans. 42(16), 5818-25, (2013)

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Photoinduced proton and charge transfer in 2-(2'-hydroxyphenyl)imidazo[4,5-b]pyridine. Brenlla A, Veiga M, Pérez Lustres JL, et al. J. Phys. Chem. B 117(3), 884-96, (2013)

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Zipping and unzipping of a paddlewheel metal-organic framework to enable two-step synthetic and structural transformation. Smart P, Mason CA, Loader JR, et al. Chemistry 19(11), 3552-7, (2013)

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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Giulia Caron et al J. Med. Chem. 48, 3269-79, (2005)

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Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes. Shimada T and Guengerich FP Cancer Res. 51(19), 5284-91, (1991)

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Assay at low ppm level of dimethyl sulfate in starting materials for API synthesis using derivatization in ionic liquid media and LC-MS. Grinberg N, Albu F, Fandrick K, et al. J. Pharm. Biomed. Anal. 75, 1-6, (2013)

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Reactions between atomic chlorine and pyridine in solid para-hydrogen: infrared spectrum of the 1-chloropyridinyl (C5H5N-Cl) radical. Das P, Bahou M, and Lee YP J. Chem. Phys. 138(5), 054307, (2013)

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Toward prediction of alkane/water partition coefficients. Anita Toulmin et al J. Med. Chem. 51, 3720-30, (2008)

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Stabilization of oxidovanadium(IV) by organic radicals. Kundu S, Maity S, Maity AN, et al. Dalton Trans. 42(13), 4586-601, (2013)

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Development of novel molecular probes of the Rio1 atypical protein kinase. Mielecki M, Krawiec K, Kiburu I, et al. Biochim. Biophys. Acta 1834(7), 1292-301, (2013)

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Biotreatment of waste gas containing pyridine in a biofilter. Pandey RA, Padoley KV, Mukherji SS, et al. Bioresour. Technol. 98(12), 2258-67, (2007)

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An efficient microwave-assisted Suzuki reaction using a new pyridine-pyrazole/Pd(II) species as catalyst in aqueous media. Shen L, Huang S, Nie Y, et al. Molecules 18(2), 1602-12, (2013)

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Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients. Fairbanks LD, Jacomelli G, Micheli V, et al. Biochem. J. 366(Pt 1), 265-72, (2002)

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QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT). Sylvie Mavel et al Bioorg. Med. Chem. 20, 1388-95, (2012)

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Synthesis and X-ray crystal structure of isomeric pyridine-based leuco-TAM dyes, 2,2-(2-(pyridinyl)propane-1,3-diylidene)bis(5-chloro-1,3,3-trimethyl indoline) derivatives and unusual stability of 4-pyridinyl compound. Ma SY and Keum SR Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 113, 261-7, (2013)

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Characterization of hydrogen peroxide removal reaction by hemoglobin in the presence of reduced pyridine nucleotides. Masuoka N, Kodama H, Abe T, et al. Biochim. Biophys. Acta 1637(1), 46-54, (2003)

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Determination of felodipine, its enantiomers, and a pyridine metabolite in human plasma by capillary gas chromatography with mass spectrometric detection. Dru JD, Hsieh JY, Matuszewski BK, et al. J. Chromatogr. B, Biomed. Appl. 666(2), 259-67, (1995)

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Conversion of pyridine to imidazo[1,2-a]pyridines by copper-catalyzed aerobic dehydrogenative cyclization with oxime esters. Huang H, Ji X, Tang X, et al. Org. Lett. 15(24), 6254-7, (2013)

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Aggregates of a triphenylene based chemosensing ensemble for sensitive detection of cyanide ions in an aqueous medium. Bhalla V, Arora H, and Kumar M Dalton Trans. 42(13), 4450-5, (2013)

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Artificial receptors inspired by crystal structures of complexes formed between acyclic receptors and monosaccharides: design, syntheses, and binding properties. Lippe J and Mazik M J. Org. Chem. 78(18), 9013-20, (2013)

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Development of a tailor-made bis(oxazolidine)pyridine-metal catalyst for the [3+2] cycloaddition of azomethine imines with propiolates. Arai T, Ogino Y, and Sato T Chem. Commun. (Camb.) 49(71), 7776-8, (2013)

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Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates. Chen JJ, et al. PLoS ONE 4(3), e4949, (2009)

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Alpha,beta-elimination reaction of O-acetylserine sulfhydrylase. Is the pyridine ring required? Cook PF Biochim. Biophys. Acta 1647(1-2), 66-9, (2003)

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In vitro dissolution of cholesterol gallstones. Sternal RS and Davis MA Invest. Radiol. 27(12), 1040-3, (1992)

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Photocatalytic degradation of N-heterocyclic aromatics-effects of number and position of nitrogen atoms in the ring. Kaur J and Pal B Environ. Sci. Pollut. Res. Int. 20(6), 3956-64, (2013)

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Hydrogen-bonding linkage of thymidine derivatives with carboxylic acid and pyridyl groups in a crystalline state. Hoshino J, Kuwabara J, and Kanbara T J. Nanosci. Nanotechnol. 13(7), 4593-600, (2013)

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Theoretical investigation on ruthenium tetraazaporphyrin as potential nitric oxide carrier in biological systems. Lima JM, Silva VH, Camargo LT, et al. J. Mol. Model. 19(4), 1727-37, (2013)

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Fluorescence emission properties of C60 nanoparticles. Zhang F, Fang Y, and Zhang X Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 106, 242-6, (2013)

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Synergistic photocatalytic degradation of pyridine using precious metal supported TiO2 with KBrO3. Tian F, Zhu R, and Ouyang F J. Environ. Sci. (China) 25(11), 2299-305, (2013)

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Physicochemical characterization of the comb-type pyridine-co-poly(ethylene glycol) copolymer at the interface. Otsuka H, Fukaishi M, Ishizuka T, et al. J. Nanosci. Nanotechnol. 13(1), 537-44, (2013)

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Self-organized CdSe quantum dots onto the low bandgap 3-hexylthiophene/pyridine copolymers. Wang J, Luo X, Kang D, et al. J. Nanosci. Nanotechnol. 13(1), 523-8, (2013)

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Synthesis, characterization, crystal structure, and biological studies of two new Cd (II) complexes with 4'-(4-chlorophenyl)-2,2' :6',2"-terpyridine (Clphtpy). Saghatforoush L, Rudbari HA, Nicolò F, et al. Acta Chim. Slov. 60(2), 300-9, (2013)

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Merck 14,7970

Beil. 20,V,5,160

Fieser 1,958 / Fieser 2,349 / Fieser 4,414 / Fieser 6,497 / Fieser 11,448 / Fieser 12,416

Aldrich MSDS 1, 1559:C / Arctander, 2776 / Corp MSDS 1 (2), 2989:D / FT-IR 1 (2), 729:A / FT-IR 2 (3), 3698:A / FT-NMR 1 (3), 233:A / Fenaroli / IR-Spectra (2), 1138:A / IR-Spectra (3), 1306:A / NMR-Reference 2 (2), 611:A / RegBook 76 (2), 2489:A / RegBook 1 (2), 2489:A / Sax 6, 2325 / Structure Index 1, 393:A:1 / Vapor Phase 3, 1513:A

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