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27242 Sigma-Aldrich

Trichloroacetic acid

puriss., meets analytical specification of Ph. Eur., USP 21, 99-100.5% (calc. to the dried substance)

Synonym: TCA

  • CAS Number 76-03-9

  • Linear Formula Cl3CCOOH

  • Molecular Weight 163.39

  •  Beilstein Registry Number 970119

  •  EC Number 200-927-2

  •  MDL number MFCD00004177

  •  PubChem Substance ID 24856470

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Properties

Related Categories Acids, Acids & Bases, Chemical Synthesis, Organic Acids, Synthetic Reagents More...
vapor density   <1 (vs air)
vapor pressure   1 mmHg ( 51 °C)
InChI Key   YNJBWRMUSHSURL-UHFFFAOYSA-N
grade   puriss.
assay   99-100.5% (calc. to the dried substance)
quality   meets analytical specification of Ph. Eur., USP 21
ign. residue   ≤0.02% (as SO4)
loss   ≤0.5% loss on drying, 18 h (on silica gel)
refractive index   n20/D 1.62(lit.)
bp   196 °C(lit.)
mp   54-58 °C(lit.)
solubility   : soluble81.7 g/L at 20 °C (completely)
density   1.62 g/mL at 25 °C(lit.)
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤500 mg/kg
cation traces   Fe: ≤20 mg/kg

Description

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1839 8 / PGII
WGK Germany 
2
RTECS 
AJ7875000
Flash Point(F) 
>235.4 °F
Flash Point(C) 
>113 °C
Protocols & Articles

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