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27242 Sigma-Aldrich

Trichloroacetic acid

puriss., meets analytical specification of Ph. Eur., USP 21, 99-100.5% (calc. to the dried substance)

Synonym: TCA

  • CAS Number 76-03-9

  • Linear Formula Cl3CCOOH

  • Molecular Weight 163.39

  •  Beilstein Registry Number 970119

  •  EC Number 200-927-2

  •  MDL number MFCD00004177

  •  PubChem Substance ID 57648227

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Properties

Related Categories Acids, Acids & Bases, Chemical Synthesis, Organic Acids, Synthetic Reagents More...
vapor density   <1 (vs air)
vapor pressure   1 mmHg ( 51 °C)
InChI Key   YNJBWRMUSHSURL-UHFFFAOYSA-N
grade   puriss.
assay   99-100.5% (calc. to the dried substance)
quality   meets analytical specification of Ph. Eur., USP 21
ign. residue   ≤0.02% (as SO4)
loss   ≤0.5% loss on drying, 18 h (on silica gel)
refractive index   n20/D 1.62(lit.)
bp   196 °C(lit.)
mp   54-58 °C(lit.)
solubility   : soluble 81.7 g/L at 20 °C (completely)
density   1.62 g/mL at 25 °C(lit.)
anion traces   chloride (Cl-): ≤50 mg/kg
  sulfate (SO42-): ≤500 mg/kg
cation traces   Fe: ≤20 mg/kg

Description

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1839 8 / PGII
WGK Germany 
2
RTECS 
AJ7875000
Flash Point(F) 
>235.4 °F
Flash Point(C) 
>113 °C
Protocols & Articles

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Peer-Reviewed Papers
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