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31493 Sigma-Aldrich

Sodium salicylate

puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Synonym: 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

  • CAS Number 54-21-7

  • Linear Formula HOC6H4COONa

  • Molecular Weight 160.10

  •  Beilstein Registry Number 3732792

  •  EC Number 200-198-0

  •  MDL number MFCD00002440

  •  PubChem Substance ID 57648580

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Properties

Related Categories Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography, Essential Chemicals, Puriss p.a.,
grade   Reag. Ph. Eur.
InChI Key   ABBQHOQBGMUPJH-UHFFFAOYSA-M
grade   puriss. p.a.
assay   99.5-101.0% (calc. to the dried substance)
impurities   acidic reac. impurities, complies
  sulfite or thiosulfate, complies
  ≤0.001% heavy metals (as Pb)
loss   ≤0.3% loss on drying, 105 °C
mp   >300 °C(lit.)
anion traces   chloride (Cl-): ≤20 mg/kg
  sulfate (SO42-): ≤500 mg/kg
cation traces   Fe: ≤10 mg/kg
suitability   in accordance for appearance of solution

Description

Application

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia. It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from the mixed micelles [composed of Pluronic P105 (P105) and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)].

General description

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
Protocols & Articles
Peer-Reviewed Papers
15

References

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