33108 Sigma-Aldrich

Chromeazurol S

indicator for metal titration

Synonym: Chrome Azurol S, Mordant Blue 29

  • CAS Number 1667-99-8

  • Empirical Formula (Hill Notation) C23H13Cl2Na3O9S

  • Molecular Weight 605.28

  •  Beilstein Registry Number 4110655

  •  Colour Index Number 43825

  •  EC Number 216-787-0

  •  MDL number MFCD00001615

  •  PubChem Substance ID 24859932



grade   indicator for metal titration


General description

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Other Notes

Same product — same quality — now Sigma-Aldrich brand

Price and Availability

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 


Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers


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Hydrolysis and speciation of Al bound to pectin and plant cell wall material and its reaction with the dye chrome azurol S. Wehr JB, Blamey FP, Hanna JV, et al. J. Agric. Food Chem. 58(9), 5553-60, (2010)


Application of cotton as a solid phase extraction sorbent for on-line preconcentration of copper in water samples prior to inductively coupled plasma optical emission spectrometry determination. Faraji M, Yamini Y, and Shariati S J. Hazard. Mater. 166(2-3), 1383-8, (2009)


Using enantioselective indicator displacement assays to determine the enantiomeric excess of alpha-amino acids. Leung D, Folmer-Andersen JF, Lynch VM, et al. J. Am. Chem. Soc. 130(37), 12318-27, (2008)


Effects of inoculation of plant-growth promoting bacteria on Ni uptake by Indian mustard. Rajkumar M and Freitas H Bioresour. Technol. 99(9), 3491-8, (2008)


Transitioning enantioselective indicator displacement assays for alpha-amino acids to protocols amenable to high-throughput screening. Leung D and Anslyn EV J. Am. Chem. Soc. 130(37), 12328-33, (2008)


Halloysite nanotubule clay for efficient water purification. Zhao Y, Abdullayev E, Vasiliev A, et al. J. Colloid. Interface Sci. 406, 121-9, (2013)


The exbD gene of Photorhabdus temperata is required for full virulence in insects and symbiosis with the nematode Heterorhabditis. Watson RJ, Joyce SA, Spencer GV, et al. Mol. Microbiol. 56(3), 763-73, (2005)


Characterization of disposable optical sensors for heavy metal determination. Vuković J, Avidad MA, and Capitán-Vallvey LF Talanta 94, 123-32, (2012)


Determination of albumin in bronchoalveolar lavage fluid by flow-injection fluorometry using chromazurol S. Sato T, Saito Y, Chikuma M, et al. Biol. Pharm. Bull. 31(3), 336-9, (2008)


Simultaneous spectrophotometric determination of binary mixtures of surfactants using continuous wavelet transformation. Afkhami A, Nematollahi D, Madrakian T, et al. J. Hazard. Mater. 166(2-3), 770-5, (2009)


O-CAS, a fast and universal method for siderophore detection. Pérez-Miranda S, Cabirol N, George-Téllez R, et al. J. Microbiol. Methods 70(1), 127-31, (2007)


Characterization of fig operon mutants of Francisella novicida U112. Kiss K, Liu W, Huntley JF, et al. FEMS Microbiol. Lett. 285(2), 270-7, (2008)


Iron acquisition mechanisms of Flavobacterium psychrophilum. Møller JD, Ellis AE, Barnes AC, et al. J. Fish Dis. 28(7), 391-8, (2005)


Tenacibactins A-D, hydroxamate siderophores from a marine-derived bacterium, Tenacibaculum sp. A4K-17. Jang JH, Kanoh K, Adachi K, et al. J. Nat. Prod. 70(4), 563-6, (2007)


Virulence factors and pathogenicity of Hafnia alvei for gilthead seabream, Sparus aurata L. Padilla D, Real F, Gómez V, et al. J. Fish Dis. 28(7), 411-7, (2005)


Identification and analysis of a siderophore biosynthetic gene cluster from Agrobacterium tumefaciens C58. Rondon MR, Ballering KS, and Thomas MG Microbiology 150(Pt 11), 3857-66, (2004)


Metachelins, mannosylated and N-oxidized coprogen-type siderophores from Metarhizium robertsii. Krasnoff SB, Keresztes I, Donzelli BG, et al. J. Nat. Prod. 77(7), 1685-92, (2014)


Identification of erythrobactin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea. Oliveira PH, Batagov A, Ward J, et al. Lett. Appl. Microbiol. 42(4), 375-80, (2006)


Cytochrome c4 is required for siderophore expression by Legionella pneumophila, whereas cytochromes c1 and c5 promote intracellular infection. Yip ES, Burnside DM, and Cianciotto NP Microbiology 157(Pt 3), 868-78, (2011)


Ornicorrugatin, a new siderophore from Pseudomonas fluorescens AF76. Matthijs S, Budzikiewicz H, Schäfer M, et al. Z. Naturforsch., C, J. Biosci. 63(1-2), 8-12, (2008)


Hydroxamate siderophores of Scedosporium apiospermum. Bertrand S, Larcher G, Landreau A, et al. Biometals 22(6), 1019-29, (2009)


Cathodic adsorptive stripping voltammetric determination of trace amounts of uranium (VI) based on its complex with Chromazorul-S. Mohadesi A, Hosseinzadeh L, Abbasi S, et al. J. AOAC Int. 92(3), 927-32, (2009)


Spectrophotometric determination of anthracycline anticancer agents with aluminum(III) and chromazurol S in a nonionic surfactant micellar medium. Nakao M, Yamazaki C, Tominaga H, et al. Anal. Sci. 22(2), 313-6, (2006)


Composition-ratio determination of Chrome Azurol S (CAS) with Cu(2+) and research on dynamic reaction process of CAS with EDTA. Liu R, Li L, Tian Y, et al. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 71(3), 1021-6, (2008)


Siderophore activity among members of the Legionella genus. Starkenburg SR, Casey JM, and Cianciotto NP Curr. Microbiol. 49(3), 203-7, (2004)


[Partial least-squares regression analysis for simultaneous spectrophotometric determination of Fe3+ and Al3+]. Peng SC, Huang CH, Chen TH, et al. Guang Pu Xue Yu Guang Pu Fen Xi 25(6), 942-4, (2005)


[Simple screening method for judging the complex formation between drug and aluminum (III)]. Miyachi K, Nakao M, Kurokawa H, et al. Yakugaku Zasshi 129(12), 1551-8, (2009)


Beil. 11,IV,707

FT-IR 2 (3), 4128:B / FT-IR 1 (2), 1032:B / IR-Spectra (3), 1484:H / RegBook 1 (2), 2775:E / Sigma FT-IR 1 (2), 115:C / Stains and Dyes Ref, 203 / Structure Index 1, 441:B:1

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