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34660 Sigma-Aldrich

Di-tert-butyl dicarbonate

≥98.0% (GC)

Synonym: Boc anhydride, Di-tert-butyl pyrocarbonate

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Properties

Related Categories Amine Protection, Chemical Biology, Chemical Synthesis, Other Protecting and Derivatizing Reagents, Peptide Chemistry,
InChI Key   DYHSDKLCOJIUFX-UHFFFAOYSA-N
assay   ≥98.0% (GC)
refractive index   n20/D 1.409(lit.)
bp   56-57 °C/0.5 mmHg(lit.)
mp   22-26 °C
  23 °C(lit.)
density   0.95 g/mL at 25 °C(lit.)
storage temp.   2-8°C

Description

Application

Reagent for the introduction of the Boc protecting group.

Other Notes

Reagent for the clean and rapid introduction of the acid labile BOC-protecting group in amino acids, peptides and proteins; N-BOC-ylation of amides; N-BOC-ylation of sensitive compounds under non-aqueous conditions.

Same product — same quality — now Sigma-Aldrich brand

Packaging

25, 100, 500 g in poly bottle

Warning

Hydrolyzes to t-butanol and CO2; causes internal pressure in bottle if exposed to moisture.

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2929 3(6.1) / PGII
WGK Germany 
3
RTECS 
HT0230000
Flash Point(F) 
98.6 °F
Flash Point(C) 
37 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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