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36650 Sigma-Aldrich

DCC

puriss., ≥99.0% (GC)

Synonym: N,N′-Dicyclohexylcarbodiimide

  • CAS Number 538-75-0

  • Linear Formula C6H11N=C=NC6H11

  • Molecular Weight 206.33

  •  Beilstein Registry Number 610662

  •  EC Number 208-704-1

  •  MDL number MFCD00011659

  •  PubChem Substance ID 329755430

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Properties

Related Categories Carbodiimides, Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry,
InChI Key   QOSSAOTZNIDXMA-UHFFFAOYSA-N
grade   puriss.
assay   ≥99.0% (GC)
bp   122-124 °C/6 mmHg(lit.)
mp   34-35 °C(lit.)
  34.5-37.0 °C
solubility   methylene chloride: soluble0.1 g/mL, clear, colorless
Gene Information   human ... EPHX2(2053)
mouse ... Ephx2(13850)

Description

Other Notes

Coupling reagent, reagent for dehydrations etc. Modifies bovine heart mitochondrial transhydrogenase; Inhibition of F1F0-ATPase and other proton-translocating enzymes

Packaging

100, 500 g in poly bottle

2.5 kg in poly bottle

Price and Availability


Laboratory Gloves

Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
RTECS 
FF2160000
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Coupling Reagents

In principle, the seemingly simple formation of a peptide bond can be accomplished using all the procedures available in organic chemistry for the synthesis of carboxylic acid amides. However, due to...
Matthias Junkers
Aldrich ChemFiles 2007, 7.2, 3.
Keywords: Acylations, Catalysis, Condensations, Dehydration reaction, Peptide synthesis, Racemizations, Solid phase peptide synthesis

Peer-Reviewed Papers
15

References

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