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366919 Sigma-Aldrich

Chloroform

ACS spectrophotometric grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Synonym: Methylidyne trichloride, Trichloromethane

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Properties

Related Categories Amber Glass Bottles, Chloroform, Solvent by Type, Solvent Bottles, Solvent Packaging Options,
grade   ACS spectrophotometric grade
vapor density   4.1 (vs air)
vapor pressure   160 mmHg ( 20 °C)
assay   ≥99.8%
contains   0.5-1.0% ethanol as stabilizer
impurities   Acetone and aldehyde, passes test
  Acid and chloride, passes test
  Free chlorine (Cl), passes test
  H2SO4, passes test (darkened)
  <0.03% water
evapn. residue   <0.001%
color   APHA: ≤10
refractive index   n20/D 1.445(lit.)
bp   60.5-61.5 °C(lit.)
mp   −63 °C(lit.)
density   1.48 g/mL at 25 °C (represents the value for the density of chloroform with ethanol stabilizer)
  1.492 g/mL at 25 °C(lit.)
cation traces   Pb: ≤0.05 ppm
λ   H2O reference
UV absorption   λ: 245 nm Amax: 1.00
  λ: 255 nm Amax: 0.25
  λ: 260 nm Amax: 0.15
  λ: 270 nm Amax: 0.05
  λ: 290-400 nm Amax: 0.01

Description

Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.

Packaging

1, 6×1, 2 L in glass bottle

Application

Chloroform (spectrophotometric grade) was used in the following processes:
• Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
• Preparing phospholipid solutions.
• As a solvent in the photolysis reaction of ruthenium complexes.
It may be used as:
• Solvent for recrystallization.
• Reference compound to detect the presence of chloroform in Tobacco smokes.
• Extractant in solvent extraction process.

General description

Chloroform is a is a colorless, volatile chlorinated organic solvent whose vapors have narcotic effect. It is susceptible to degradation with time which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Spectrophotometric grade chloroform shows low UV absorption which makes it an ideal solvent for spectrophotometry.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
RIDADR 
UN 1888 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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