383120 Sigma-Aldrich

Sulfamic acid

ACS reagent, 99.3%

Synonym: Amidosulfonic acid



Related Categories Acids, Acids & Bases, Chemical Synthesis, Inorganic Acids, Synthetic Reagents More...
grade   ACS reagent
assay   99.3%
  99.3-100.3% dry basis (ACS specification)
impurities   ≤0.01% insolubles
ign. residue   ≤0.01%
mp   215-225 °C (dec.)(lit.)
solubility   water: soluble213 g/L at 20 °C
anion traces   chloride (Cl-): ≤0.001%
  sulfate (SO42-): ≤0.05%
cation traces   Fe: ≤5 ppm
  heavy metals (as Pb): ≤0.001%
Gene Information   human ... CA1(759), CA2(760)


Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.


100, 500 g in poly bottle


Sulfamic acid (H2NSO3H) may be used in the following studies:
• As catalyst in the synthesis of aryl-14H-dibenzo[a.j]xanthenes.
• As green catalyst for the preparation of amide from ketoxime.
• As ammonia equivalent in the regioselective synthesis of primary allylic amines, via allylic substitution reactions.
• Synthesis of polysubstituted quinolones.

Sulfamic acid may be used in the following processes:
• As a titrant in the determination of the burette injection volume and chemical calibration factor.
• To neutralize excess nitrous acid in the colorimetric paracetamol assay by modified Glynn and Kendal colorimetric method.
• To prevent endogenous mercury (Hg) loss during the urine Hg measurement by inductively coupled plasma mass spectrometry (ICP-MS) method.
• As an acid catalyst and a hypochlorite scavenger in the chlorite oxidation of dialdehyde cellulose (DAC).
• As a heterogeneous catalyst in the synthesis of polyhydroquinoline derivatives by Hantzsch condensation reaction.
• As catalyst in the degradation of bamboo fiber to 5-hydroxymethylfurfural (HMF).
• As an acid reagent in the determination of silicates in water samples based on centrifugal microfluidics.
• As catalyst in the synthesis of deazaoxaflavin at room temperature.

General description

Sulfamic acid (H2NSO3H) is widely used inorganic compound. It exists in zwitterionic form and neutral forms. Zwitterionic form has been reported to be is more stable than neutral form. Its industrial applications have been reported. It has various organic synthesis applications.

Sulfamic acid is a strong inorganic acid. It is a hypochlorite scavenger. The ability of sulfamic acid to reduce nitrate to nitrogen gas under acidic condition has been utilized to denitrify nitrate-rich wastewater along with zinc powder.

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
UN 2967 8 / PGIII
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


EPA Method 335.4 Product Selection Guide

This product selection guide is designed to simplify the ordering of products for EPA Method 335.4. This method is for the determination of total cyanide in various water and waste samples.

Related Content

Molarity Calculator and Normality Calculator for Acids and Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution.  To...

Peer-Reviewed Papers


Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?