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39380 Sigma-Aldrich

3-(Dimethylamino)-1-propylamine

purum, ≥98.0% (GC)

Synonym: N,N-Dimethyl-1,3-diaminopropane, N,N-Dimethyl-1,3-propanediamine

  • CAS Number 109-55-7

  • Linear Formula (CH3)2N(CH2)3NH2

  • Molecular Weight 102.18

  •  Beilstein Registry Number 605293

  •  EC Number 203-680-9

  •  MDL number MFCD00008216

  •  PubChem Substance ID 329755864

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Properties

Related Categories Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Polyamines More...
vapor density   3.6 (vs air)
vapor pressure   5 mmHg ( 20 °C)
InChI Key   IUNMPGNGSSIWFP-UHFFFAOYSA-N
grade   purum
assay   ≥98.0% (GC)
impurities   ≤2% water
refractive index   n20/D 1.435(lit.)
  n20/D 1.436
bp   133 °C(lit.)
density   0.812 g/mL at 25 °C(lit.)

Description

Other Notes

Industrial applications

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Application

3-(Dimethylamino)-1-propylamine (DMAPA) is suitable reagent used in the following studies:
• As a cationic moiety to form the ionic liquid, 3-(dimethylamino)-1-propylaminium formate ([DMAPA]FA) which is a potential reagent to extract protein from yeast cells.
• As an aminating agent in the palladium-catalyzed amination of aryl amines.
• In the derivatization of pullulan to form cationic pullulan.
• In the partial modification of poly(styrene-alt-maleic anhydride) to form N-substituted maleimide.
• As a test compound in the parallel synthesis of alkylamine lipidoids.
• To cleave the polyamides synthesized by solid phase methods on Boc-β-Ala-PAM resin.
It may be used in the following studies:
• Synthesis of (N,N-dialkylamino)alkyl-2-amino benzamide by reacting with isatoic anhydride.
• As a reagent for the anomeric deacetylation of protected sugars.
• Preparation of bioreducible copolymers used in gene delivery.

General description

3-(Dimethylamino)-1-propylamine (DMAPA, N,N-dimethyl-1,3-propanediamine) is a dialkylamino alkyl amine. It has been prepared from dimethylamine and acrylonitrile and confirmed by 1H NMR. It participates in the synthesis of bio-based zwitterionic surfactants from waste cooking oil (WCO).

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2734PSN2 3(8) / PGII
WGK Germany 
1
RTECS 
TX7525000
Flash Point(F) 
89.6 °F
Flash Point(C) 
32 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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