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437573 Sigma-Aldrich

N,N-Dimethylformamide

ACS reagent, ≥99.8%

Synonym: DMF, NSC 5356

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Properties

Related Categories ACS Grade, ACS Grade Solvents, ACS and Reagent Grade Solvents, Dimethylformamide (DMF), PVC Coated Bottles,
grade   ACS reagent
vapor density   2.5 (vs air)
vapor pressure   2.7 mmHg ( 20 °C)
InChI Key   ZMXDDKWLCZADIW-UHFFFAOYSA-N
assay   ≥99.8%
form   liquid
autoignition temp.   833 °F
expl. lim.   15.2 %
impurities   ≤0.0005 meq/g Titr. acid
  ≤0.003 meq/g Titr. base
  ≤0.15% water
evapn. residue   ≤0.005%
color   APHA: ≤15
refractive index   n20/D 1.430(lit.)
bp   153 °C(lit.)
mp   −61 °C(lit.)
solubility   water: miscible
density   0.944 g/mL(lit.)

Description

Application

Solvent for many hydrophobic organic compounds.

N,N-Dimethylformamide (DMF) may be used in the following processes:
• As a solvent synthesis of gold nanoparticles.
• As a solvent in capillary electrophoresis.
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.

Packaging

18 L in VerSA-Flow™

4×4 L in PVC-coated bottle

General description

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2265 3 / PGIII
WGK Germany 
2
RTECS 
LQ2100000
Flash Point(F) 
136.4 °F
Flash Point(C) 
58 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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