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  • 44239 - Dodecyltrimethylammonium bromide


44239 Sigma-Aldrich

Dodecyltrimethylammonium bromide

for ion pair chromatography, ≥98.5% (AT)

Synonym: Lauryltrimethylammonium bromide

  • CAS Number 1119-94-4

  • Linear Formula CH3(CH2)11N(CH3)3Br

  • Molecular Weight 308.34

  •  Beilstein Registry Number 3597463

  •  EC Number 214-290-3

  •  MDL number MFCD00011767

  •  PubChem Substance ID 24867824



Related Categories Acidic Ion Pair Reagents (Anionic), Analytical Reagents, Analytical/Chromatography, Biochemicals and Reagents, Buffers & Reagents,
grade   for ion pair chromatography
description   cationic
assay   ≥98.5% (AT)
mp   246 °C (dec.)(lit.)
λ   10 % in H2O
UV absorption   λ: 240 nm Amax: ≤0.2
  λ: 250 nm Amax: ≤0.03
  λ: 260 nm Amax: ≤0.02
  λ: 500 nm Amax: ≤0.02
suitability   corresponds to standard for filter test


Other Notes

Same product — same quality — now Sigma-Aldrich brand

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Safety & Documentation

Safety Information

Signal word 
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Personal Protective Equipment 
UN 3077 9 / PGIII
WGK Germany 


Certificate of Analysis

Protocols & Articles

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Peer-Reviewed Papers


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Excited-state intramolecular hydrogen atom transfer of curcumin in surfactant micelles. Adhikary R, Carlson PJ, Kee TW, et al. J. Phys. Chem. B 114(8), 2997-3004, (2010)


Aqueous phase behavior of polyelectrolytes with amphiphilic counterions modulated by cyclodextrin: the role of polyion flexibility. Carlstedt J, Bilalov A, and Olsson U Phys. Chem. Chem. Phys. 14(27), 9574-7, (2012)


Microfluidic sensing devices employing in situ-formed liquid crystal thin film for detection of biochemical interactions. Liu Y, Cheng D, Lin IH, et al. Lab Chip 12(19), 3746-53, (2012)


A study on the effect of surface lysine to arginine mutagenesis on protein stability and structure using green fluorescent protein. Sokalingam S, Raghunathan G, Soundrarajan N, et al. PLoS ONE 7(7), e40410, (2012)


Spectrometric study on the interaction of dodecyltrimethylammonium bromide with curcumin. Ke D, Wang X, Yang Q, et al. Langmuir 27(23), 14112-7, (2011)


Solubilization of two organic dyes by cationic ester-containing gemini surfactants. Tehrani-Bagha AR, Singh RG, and Holmberg K J. Colloid. Interface Sci. 376(1), 112-8, (2012)


Adsorption of phenolic compounds by organoclays: implications for the removal of organic pollutants from aqueous media. Park Y, Ayoko GA, Kurdi R, et al. J. Colloid. Interface Sci. 406, 196-208, (2013)


In vitro effects of cationic compounds on functional human sperm parameters. Baptista M, Publicover SJ, and Ramalho-Santos J Fertil. Steril. 99(3), 705-12, (2013)


From chain collapse to new structures: spectroscopic properties of poly(3-thiophene acetic acid) upon binding by alkyl trimethylammonium bromide surfactants. Franco IE, Lorchat P, Lamps JP, et al. Langmuir 28(10), 4815-28, (2012)


Novel screen-printed electrode for the determination of dodecyltrimethylammonium bromide in water samples. Mohamed GG, Ali TA, El-Shahat MF, et al. Drug Test. Anal. 4(12), 1009-13, (2012)


Synthesis and characterization of "hairy urchin"-like polyaniline by using β-cyclodextrin as a template. Prasannan A, Truong Tle B, Hong PD, et al. Langmuir 27(2), 766-73, (2011)


One-pot synthesis of dendritic gold nanostructures in aqueous solutions of quaternary ammonium cationic surfactants: effects of the head group and hydrocarbon chain length. Huang D, Qi Y, Bai X, et al. ACS Appl. Mater. Interfaces 4(9), 4665-71, (2012)


Electroless deposition of Ni-P-nano-ZrO2 composite coatings in the presence of various types of surfactants. Zielińska K, Stankiewicz A, and Szczygieł I J. Colloid. Interface Sci. 377(1), 362-7, (2012)


Formation of protein/surfactant adsorption layer at the air/water interface as studied by dilational surface rheology. Mikhailovskaya AA, Noskov BA, Lin SY, et al. J. Phys. Chem. B 115(33), 9971-9, (2011)


Physicochemical properties of methylcellulose and dodecyltrimethylammonium bromide in aqueous medium. Villetti MA, Bica CI, Garcia IT, et al. J. Phys. Chem. B 115(19), 5868-76, (2011)


Analysis of plasma nucleotides in rat by micellar electrokinetic capillary chromatography/electrospray ionization mass spectrometry. Bhowmik SK and Jung BH Rapid Commun. Mass Spectrom. 26(12), 1426-36, (2012)


Study on the effect of chain-length compatibility of mixed anionic-cationic surfactants on the cloud-point extraction of selected organophosphorus pesticides K Seebunrueng et al. Anal. Bioanal. Chem 404, 1539, (2012)


Bicephalic amphiphile architecture affects antibacterial activity. Jade E LaDow et al Eur. J. Med. Chem. 46, 4219-26, (2011)


Salt effect on microscopic structure and stability of colloidal complex obtained from neutral/polyelectrolyte block copolymer and oppositely charged surfactant. Annaka M Colloids Surf. B Biointerfaces 99, 127-35, (2012)


Spontaneous vesicles, disks, threadlike and spherical micelles found in the solubilization of DMPC liposomes by the detergent DTAC. Correia RF, Viseu MI, Prazeres TJ, et al. J. Colloid. Interface Sci. 379(1), 56-63, (2012)


Morphology characterization and single-molecule study of DNA-dodecyltrimethylammonium bromide complex. Ran SY, Wang YW, Yang GC, et al. J. Phys. Chem. B 115(16), 4568-75, (2011)


Nanocomposite formation between alpha-glucosyl stevia and surfactant improves the dissolution profile of poorly water-soluble drug. Uchiyama H, Tozuka Y, Nishikawa M, et al. Int. J. Pharm. 428(1-2), 183-6, (2012)


Competition of hydrophobic steroids with sodium dodecyl sulfate, dodecyltrimethylammonium bromide, or dodecyl β-D-maltoside for the dodecane/water interface. Feng S and Bummer PM Langmuir 28(49), 16927-32, (2012)


Effect of surfactant mixtures on skin structure and barrier properties. James-Smith MA, Hellner B, Annunziato N, et al. Ann. Biomed. Eng. 39(4), 1215-23, (2011)


Luciferase and fluorescent protein as dual reporters analyzing the effect of n-dodecyltrimethylammonium bromide on the physiology of Pseudomonas putida. Zhang C, Su FY, Zhang JF, et al. Appl. Microbiol. Biotechnol. 93(1), 393-400, (2012)


Denaturation and intermediates study of two sturgeon hemoglobins by n-dodecyl trimethylammonium bromide. Ariaeenejad S, Habibi-Rezaei M, Kavousi K, et al. Int. J. Biol. Macromol. 53, 107-13, (2013)


Catalytic performance and thermostability of chloroperoxidase in reverse micelle: achievement of a catalytically favorable enzyme conformation. Wang Y, Wu J, Ru X, et al. J. Ind. Microbiol. Biotechnol. 38(6), 717-24, (2011)


Beil. 4,IV,798

Aldrich MSDS 1, 848:A / Corp MSDS 1 (1), 1496:B / RegBook 1 (1), 419:B / Sigma FT-IR 1 (2), 67:A / Structure Index 1, 61:B:3

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