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44577 Sigma-Aldrich

Doxycycline hyclate

≥98.0% (TLC)

Synonym: Doxycycline hydrochloride hemiethanolate hemihydrate

  • CAS Number 24390-14-5

  • Empirical Formula (Hill Notation) C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O

  • Molecular Weight 512.94

  •  Beilstein Registry Number 5702728

  •  MDL number MFCD07357237

  •  PubChem Substance ID 329756520

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
biological source   from synthetic
InChI Key   HALQELOKLVRWRI-ZVACAFRPSA-N
assay   ≥98.0% (TLC)
form   powder
impurities   ≤5% water
  ≤7% ethanol
color   faintly yellow to yellow
solubility   H2O: 50 mg/mL clear, yellow-green
Mode of action   protein synthesis | interferes

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

This product has been replaced by D9891-SIGMA | Doxycycline hyclate ≥98% (TLC)

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Is doxycycline hyclate soluble in DMSO?
According to literature sources, doxycycline hyclate is soluble in DMSO at a concentration of 100 mM.
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Protocols & Articles
Peer-Reviewed Papers
15

References

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