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45187 Sigma-Aldrich

Endothelin 1

≥97.0% (HPLC)

Synonym: ET-1

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Properties

Related Categories Agonists, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes,
InChI Key   ZUBDGKVDJUIMQQ-ZTNLKOGPSA-N
assay   ≥97.0% (HPLC)
storage temp.   −20°C
Gene Information   human ... EDN1(1906)

Description

Amino Acid Sequence

Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp [Disulfide Bridges: 1-15; 3-11]

Other Notes

A synthetic peptide with the sequence of human and porcine Endothelin 1.

Review. Endothelins as regulators of vascular tone in man

Biochem/physiol Actions

Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.

Price and Availability


Amplified Detection

All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
KE9446500

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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E7764 Endothelin 1, ≥97% (HPLC), powder

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