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45189 Sigma-Aldrich

Endothelin 3 human, rat

≥97.0% (HPLC)

Synonym: ET-3

  • CAS Number 117399-93-6

  • Empirical Formula (Hill Notation) C121H168N26O33S4

  • Molecular Weight 2643.04

  •  MDL number MFCD00076378

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Properties

InChI Key   OQGZWNZGVYLIFX-XKIQDWPYSA-N
assay   ≥97.0% (HPLC)
storage temp.   −20°C
Gene Information   human ... EDN3(1908)

Description

Amino Acid Sequence

Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp [Disulfide Bridges: 1-15; 3-11]

Other Notes

Properties and application

Same product — same quality — now Sigma-Aldrich brand

Biochem/physiol Actions

Potent vasoconstrictor from vascular endothelial cells; preferred agonist for ETB endothelin receptors. Induces the production of VEGF.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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