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45189 Sigma-Aldrich

Endothelin 3 human, rat

≥97.0% (HPLC)

Synonym: ET-3

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Properties

InChI Key   OQGZWNZGVYLIFX-XKIQDWPYSA-N
assay   ≥97.0% (HPLC)
storage temp.   −20°C
Gene Information   human ... EDN3(1908)

Description

Amino Acid Sequence

Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp [Disulfide Bridges: 1-15; 3-11]

Other Notes

Properties and application

Biochem/physiol Actions

Potent vasoconstrictor from vascular endothelial cells; preferred agonist for ETB endothelin receptors. Induces the production of VEGF.

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Laboratory Gloves
Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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