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45710 Sigma-Aldrich

Eserine

≥98.0% (N)

Synonym: Physostigmine

  • CAS Number 57-47-6

  • Empirical Formula (Hill Notation) C15H21N3O2

  • Molecular Weight 275.35

  •  Beilstein Registry Number 91230

  •  EC Number 200-332-8

  •  MDL number MFCD00151090

  •  PubChem Substance ID 329756919

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Properties

Related Categories Acetylcholinesterase, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   PIJVFDBKTWXHHD-HIFRSBDPSA-N
assay   ≥98.0% (N)
optical activity   [α]20/D −77±1°, c = 1.7% in chloroform
mp   102-104 °C(lit.)
  102-106 °C
storage temp.   2-8°C
Gene Information   human ... ACHE(43), APP(351), BCHE(590)
mouse ... Ache(11423), Bche(12038), Chrm1(12669)
rat ... Ache(83817), Bche(65036), Chrm2(81645)

Description

Biochem/physiol Actions

Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.

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Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1544PSN1 6.1 / PGI
WGK Germany 
3
RTECS 
TJ2100000
Flash Point(F) 
>212 °F
Flash Point(C) 
>100 °C

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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