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46713 Sigma-Aldrich

Rifampicin

VETRANAL, analytical standard

Synonym: 3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP

  • CAS Number 13292-46-1

  • Empirical Formula (Hill Notation) C43H58N4O12

  • Molecular Weight 822.94

  •  Beilstein Registry Number 5723476

  •  EC Number 236-312-0

  •  MDL number MFCD00151389

  •  PubChem Substance ID 329757224

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Antibacterial, Antibiotics,
grade   analytical standard
InChI Key   JQXXHWHPUNPDRT-WLSIYKJHSA-N
product line   VETRANAL
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   mycobacteria
format   neat
storage temp.   2-8°C

Description

Biochem/physiol Actions

Inhibits the assembly of DNA and protein into mature virus particles.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a trademark of Sigma-Aldrich Co. LLC

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
VJ7000000

Documents

Certificate of Analysis

Protocols & Articles

Articles

Inhibition of Nucleic Acid Synthesis by Antibiotics

Quinolones are a key group of antibiotics that interfere with DNA synthesis by inhibiting topoisomerase, most frequently topoisomerase II (DNA gyrase), an enzyme involved in DNA replication. DNA gyra...
BioFiles 2006, 1.4, 7.
Keywords: Antibiotics, Antitumor agents, Cancer, DNA replication

Peer-Reviewed Papers
15

References

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