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471712 Sigma-Aldrich

tert-Butanol

anhydrous, ≥99.5%

Synonym: 2-Methyl-2-propanol, tert-Butyl alcohol, Trimethyl carbinol

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Properties

Related Categories Anhydrous Solvents, Solvent Bottles, Solvent Packaging Options, Solvent by Application, Solvents,
grade   anhydrous
vapor density   2.5 (vs air)
vapor pressure   31 mmHg ( 20 °C)
  44 mmHg ( 26 °C)
InChI Key   DKGAVHZHDRPRBM-UHFFFAOYSA-N
assay   ≥99.5%
autoignition temp.   896 °F
expl. lim.   8 %
impurities   <0.005% water
evapn. residue   <0.0003%
refractive index   n20/D 1.387(lit.)
bp   83 °C(lit.)
mp   23-26 °C(lit.)
solubility   water: miscible
density   0.775 g/mL at 25 °C(lit.)

Description

Packaging

100 mL in Sure/Seal™

General description

tert-Butanol (tBA) is a tertiary alcohol. It undergoes dehydration by reactive distillation in the presence of solid acid catalyst to form isobutylene with high selectivity. Lipase-mediated alcoholysis of soybean oil deodorizer distillate (SODD) has been conducted in tBA (as reaction medium) to generate biodiesel. Formation of 2-tert-butyl-p-cresol (TBC), 2,6-di-tert-butyl-p-cresol (DTBC) and tert-butyl-p-tolyl ether has been reported when p-cresol undergoes butylation by tBA in the presence of 12-tungstophosphoric acid supported on zirconia (TPA/ZrO2) catalyst. The interaction behavior of tBA on the Si (001)-(2×1) surface has been assessed by using the ab-initio density functional theory (DFT) based on pseudopotential approach.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN1120 - class 3 - PG 2 - Butanols
WGK Germany 
1
RTECS 
EO1925000
Flash Point(F) 
51.8 °F
Flash Point(C) 
11 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles-

Pd2(dba)3/tris(tert-butyl)�HBF4/KF�2H2O serves as a mild, robust, and user-friendly method for the efficient Suzuki cross-coupling of a diverse array of aryl and heteroaryl halides with aryl- and het...
Keywords: Chromatography, Cross couplings, Flash chromatography

Cross-Coupling of Mesylated Phenol Derivatives with Potassium Cyclopropyltrifluoroborate

A robust and efficient protocol for the introduction of the dioxolanylethyl moiety onto various aryl and heteroaryl halides has been developed, providing cross-coupling yields up to 93%. Copper-catal...
Keywords: Catalysis, Chromatography, Cross couplings, Flash chromatography, Purification

Palladium-Catalyzed N-Arylation of 2-Aminothiazoles

The chemoselective and complementary Pd- and Cu-catalyzed N-arylation of 2-aminobenzimidazoles is described. Selective N-arylation of the amino group was achieved with a Pd-catalyzed method, while se...
Keywords: Arylations, Catalysis, Chromatography, Flash chromatography

Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases

We report our studies on the use of two catalyst systems, based on the ligands BrettPhos and RuPhos, which provide the widest scope for Pd-catalyzed C-N cross-coupling reactions to date. Often low ca...
Keywords: Arylations, Catalysis, Coupling reactions, Cross couplings, Ligands, Pharmaceutical

Synthesis and Application of Palladium Precatalysts that Accommodate Extremely Bulky Di-tert-butylphosphino Biaryl Ligands

An umpolung approach to the synthesis of diaryl ketones has been developed based on in situ generation of acyl anion equivalents and their catalytic arylation. This method entails the base-promoted, ...
Keywords: Arylations, Catalysis, Chromatography, Cross couplings, Flash chromatography

Peer-Reviewed Papers
15

References

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