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49909 Sigma-Aldrich

Lanolin

tested according to Ph.Eur.

Synonym: Adeps lanae, Wool fat

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Properties

Related Categories Biochemicals and Reagents, Core Bioreagents, Lipids, Lipids and Related Products, Other Lipid Related Products,
autoignition temp.   833 °F
pharmacopeia   testing conforms to Pharmacopeia

Description

Application

Lanolin was used to compose the lanolin ointment to estimate the release kinetics of izotretinon and heparin from various semisolid dosage forms by UV-VIS spectroscopy. It was used to prepare the emulsified aqueous solutions containing crystalline dicarboxylic acid. It may be added as excipient to compose a nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye.

General description

Lanolin is a wool fat. It is a semisolid of high viscosity. Contact allergy to lanolin (wool alcohols), an important sensitizer, in a central London teaching hospital patch-test population has been reported. Simplified extraction of organochlorine and organophosphorus pesticides, frequently found in lanolin, has been proposed. It is utilized as an emulsifier in pharmaceutical and cosmetic formulations.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
OE3201000
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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