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51121 Sigma-Aldrich

Guanosine 5′-triphosphate sodium salt hydrate

≥95% (HPLC)

Synonym: GTP

  • CAS Number 36051-31-7

  • Empirical Formula (Hill Notation) C10H16N5O14P3 · xNa+

  • Molecular Weight 523.18 (free acid basis)

  •  Beilstein Registry Number 3585677

  •  EC Number 252-847-2

  •  MDL number MFCD00077781

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Properties

InChI Key   KZRMTEVIDYXWQW-CYCLDIHTSA-K
assay   ≥95% (HPLC)
shipped in   wet ice
storage temp.   −20°C

Description

Other Notes

Same product — same quality — now Sigma-Aldrich brand

Biochem/physiol Actions

GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

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Safety & Documentation

Safety Information

WGK Germany 
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Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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