52245 Sigma-Aldrich


analytical standard

Synonym: Acid Red 14, Chromotrope FB, Disodium 4-hydroxy-3-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenesulfonate, Mordant Blue 79

  • CAS Number 3567-69-9

  • Empirical Formula (Hill Notation) C20H12N2Na2O7S2

  • Molecular Weight 502.43

  •  Colour Index Number 14720

  •  E Number E122

  •  EC Number 222-657-4

  •  MDL number MFCD00003978



Other Notes

Same product — same quality — now Sigma-Aldrich brand


Bottomless glass bottle. Contents are inside inserted fused cone.

Price and Availability

Suggested Laboratory Gloves

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Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
WGK Germany 


Certificate of Analysis

Protocols & Articles

Peer-Reviewed Papers


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Oro-facial granulomatosis. Response to elemental diet and provocation by food additives. Sweatman MC, Tasker R, Warner JO, et al. Clin. Allergy 16(4), 331-8, (1986)


Pattern of intake of food additives associated with hyperactivity in Irish children and teenagers. Connolly A, Hearty A, Nugent A, et al. Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 27(4), 447-56, (2010)


Toxic effects of some synthetic food colorants and/or flavor additives on male rats. El-Wahab HM and Moram GS Toxicol. Ind. Health 29(2), 224-32, (2013)


Synthetic food colourings and 'hyperactivity': a double-blind crossover study. Rowe KS Aust. Paediatr. J. 24(2), 143-7, (1988)


Effect of food azo dyes tartrazine and carmoisine on biochemical parameters related to renal, hepatic function and oxidative stress biomarkers in young male rats. Amin KA, Abdel Hameid H, and Abd Elsttar AH Food Chem. Toxicol. 48(10), 2994-9, (2010)


Effect of artificial food colours on childhood behaviour. Pollock I and Warner JO Arch. Dis. Child. 65(1), 74-7, (1990)


In vitro inhibition of phenolsulphotransferase by food and drink constituents. Gibb C, Glover V, and Sandler M Biochem. Pharmacol. 36(14), 2325-30, (1987)


Simultaneous cloud point extraction and spectrophotometric determination of carmoisine and brilliant blue FCF in food samples. Pourreza N and Ghomi M Talanta 84(1), 240-3, (2011)


Spectroscopic analysis and DFT calculations of a food additive carmoisine. Snehalatha M, Ravikumar C, Hubert Joe I, et al. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 72(3), 654-62, (2009)


Synthetic organic food colouring agents and their degraded products: effects on human and rat cholinesterases. Osman MY, Sharaf IA, Osman HM, et al. Br. J. Biomed. Sci. 61(3), 128-32, (2004)


Reduction rate of 14C-Carmoisine by resting cell bacterial suspension from human and rat faeces. Flaminio LM, Tragni E, De Giorgi A, et al. Pharmacol. Res. Commun. 20(10), 907-17, (1988)


Tartrazine induced histamine release in vivo in normal subjects. Murdoch RD, Pollock I, and Naeem S J. R. Coll. Physicians Lond. 21(4), 257-61, (1987)


Estimates of dietary exposure of children to artificial food colours in Kuwait. Husain A, Sawaya W, Al-Omair A, et al. Food Addit. Contam. 23(3), 245-51, (2006)


Microbiological research on soft drinks: discolouring of natural-flavoured products. Turtura GC and Minguzzi A Zentralbl. Mikrobiol. 147(1-2), 51-60, (1992)


Application of a radioactivity detector to the analysis of 14C-carmoisine metabolites by ion-pair high-pressure liquid chromatography. Tragni E, Costa LG, Marinovich M, et al. J. Appl. Toxicol. 4(2), 105-8, (1984)


Identification of [14C]carmoisine metabolites in bacterial suspension of rat faeces. Tragni E, Marinovich M, Ciuffreda P, et al. Food Addit. Contam. 7(1), 1-7, (1990)


Metabolic disposition of 14C-labelled carmoisine in the rat, mouse and guinea-pig. Phillips JC, Bex C, Walters DG, et al. Food Chem. Toxicol. 25(12), 927-35, (1987)


Similar profile of urinary and faecal metabolites of 14C-carmoisine in male and pregnant female rats after oral administration. Tragni E, Flaminio LM, Galli CL, et al. J. Appl. Toxicol. 5(5), 273-6, (1985)


A novel method for the determination of synthetic colors in ice cream samples. Tripathi M, Khanna SK, and Das M J. AOAC Int. 87(3), 657-63, (2004)


In vitro toxicity evaluation of a product obtained from carmoisine using Tetrahymena pyriformis cells. Marathe SA, Adhikari HR, Netrawali MS, et al. Food Chem. Toxicol. 31(10), 739-44, (1993)


Determination of vanadium in groundwater samples with an improved kinetic spectrophotometric method. Bağda E Environ. Technol. 35(9-12), 1165-74, (2014)


Noradrenaline storage function of species-specific protein bodies, markers of monoamine neurons in human locus coeruleus demonstrated by dopamine-beta-hydroxylase immunogold localization. Issidorides MR, Havaki S, Arvanitis DL, et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 28(5), 829-47, (2004)


Long-term toxicity study of carmoisine in rats using animals exposed in utero. Ford GP, Stevenson BI, and Evans JG Food Chem. Toxicol. 25(12), 919-25, (1987)


Toxicity of tomato red, a popular food dye blend on male albino mice. Sharma S, Goyal RP, Chakravarty G, et al. Exp. Toxicol. Pathol. 60(1), 51-7, (2008)


Indigotine, azorubine, and cochineal red as photoprotectors of manidipine. Mielcarek J, Grobelny P, and Osmałek T Drug Dev. Ind. Pharm. 36(3), 302-6, (2010)


"Now you see you don't." Carmoisine vital dye facilitates complete removal of cutaneous neoplasia by intraoperative visual enhancement. Murphy KD and Hall PN Br. J. Plast. Surg. 56(6), 611-3, (2003)


Beil. 16,II,129

FT-IR 2 (3), 4096:B / FT-IR 1 (2), 988:C / IR-Spectra (3), 1463:B / RegBook 1 (2), 2751:J / Sax 6, 1561 / Stains and Dyes Ref, 204 / Structure Index 1, 436:A:2

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