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52517 Sigma-Aldrich

1,1,1,3,3,3-Hexafluoro-2-propanol

for GC derivatization, ≥99.8%

Synonym: HFP, Hexafluoroisopropanol

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Derivatization Reagents, Derivatization Reagents GC, Reagents for Alkylation & Esterification More...
grade   for GC derivatization
InChI Key   BYEAHWXPCBROCE-UHFFFAOYSA-N
assay   ≥99.8% (GC)
  ≥99.8%
refractive index   n20/D 1.275(lit.)
bp   59 °C(lit.)
mp   −4 °C(lit.)
density   1.596 g/mL at 25 °C(lit.)
derivatization reagent for   Acylations
  Esterifications

Description

Application

Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid.

Other Notes

Reagent for hexafluoroisopropyl ester, N-pentafluoropropionyl, and trifluoroacetyl..

Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2-propanol

General description

Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3265 8 / PGII
WGK Germany 
2
RTECS 
UB6450000
Protocols & Articles
Peer-Reviewed Papers
15

References

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