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57577 Sigma-Aldrich

D-myo-Inositol-1,4,5-tris-phosphate pentapotassium salt from bovine brain

≥97.0% (TLC)

  • Empirical Formula (Hill Notation) C6H10K5O15P3

  • Molecular Weight 610.55

  •  MDL number MFCD00077798

  •  PubChem Substance ID 329758321

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Properties

InChI Key   CLPLHKHGSKJADP-SGNYWNPQSA-I
assay   ≥97.0% (TLC)
impurities   ≤1% D-myo-inositol-2,4,5-triphosphate
solubility   H2O: soluble25 mg/mL, clear, colorless
storage temp.   −20°C

Description

Other Notes

A second messenger in cellular signal transduction

Same product — same quality — now Sigma-Aldrich brand

Preparation Note

from 3-sn-phosphatidylinositol 4,5-bisphosphate

Biochem/physiol Actions

Ins(1,4,5)P3 has been shown to open Ca2+ channels in tonoplasts, which ares the cytoplasmic membranes that surround the vacuoles of a plant cells. The effect of Ins(1,4,5)P3 is reversible and specific when compared with other inositides.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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I7012 D-myo-Inositol 1,4,5-trisphosphate potassium salt, synthetic

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